Synthesis of Silica Based Nanoparticles Against the Proliferation of Human Prostate Cancer.

Background: Prostate cancer (PCa) has the second-highest morbidity and mortality rates in men. Possessing facile surface chemistry and unique optical properties make silica nanoparticles(SiO-NPs) promising cancer therapy materials.

Objective: This study aimed to investigate the effects of SiO-NPs and their derivatives, including SiNP-NH2, SiNP-Cl, and SiNP-SH against PCa and clarify their molecular mechanism on cell death, gene, and protein expressions.

Urease immobilized electrospun PVA/chitosan nanofibers with improved stability and reusability characteristics: an application for removal of urea from artificial blood serum.

Electrospun polyvinyl alcohol (PVA)/Chitosan nanofibers were successfully prepared and were used as carriers for the first time in urease immobilization. Also, urease immobilized electrospun PVA/Chitosan nanofibers were applied for the removal of urea from artificial blood serum by recycled reactor. The nanofibers were optimized and synthesized by electrospinning technique according to the operational parameters.

Synthesis and characterization of electrospun PVA/Zn metal composite nanofibers for lipase immobilization with effective thermal, pH stabilities and reusability.

Polyvinyl alcohol (PVA)/Zn electrospun nanofibers that were a kind of polymer/ionic metal composite was successfully embedded in the hybrid fibers for the first time in the literature, due to chemical interactions between PVA and Zn. Also, the nanofibers were used as carriers for the first time in enzyme immobilization. The nanofibers were optimized and synthesized by electrospinning technique according to the operational parameters like as PVA concentration (%), Zn concentration (%), voltage (kV), needle tip-collector distance (cm) and injection speed (ml/h).

Performance of SiO/Ag Core/Shell particles in sonocatalalytic degradation of Rhodamine B.

In this study, SiO/Ag Core/Shell nanoparticles was prepared and sonocatalytic activity of prepared catalyst was investigated by using Rhodamine B as model contaminant, at 35 kHz using ultrasonic power of 160 W within 90 min. The change in efficiency in the sonocatalytic degradation of Rhodamine B catalyzed by SiO/Ag Core/Shell nanoparticles with respect to the initial concentration of dye, catalyst amount and temperature were firstly investigated. Optimal conditions were found as follows: catalyst amount = 15 mg/L, Temperature = 25 °C and initial concentration of dye = 10 ppm.

A comparative study for lipase immobilization onto alginate based composite electrospun nanofibers with effective and enhanced stability.

In this study, lipase was successfully immobilized on polyvinyl alcohol/alginate and polyethylene oxide/alginate nanofibers that were prepared by electrospinning. Results showed that nanofibers (especially polyvinyl alcohol/alginate) enhanced the stability properties of lipase. When the free lipase lost its all activity after 40-60min at high temperatures, both lipase immobilized nanofibers kept almost 65-70% activity at the same time.

Synthesis and characterization of chitosan/TiO2 composite beads for improving stability of porcine pancreatic lipase.

The purpose of the present work is improving stability properties of porcine pancreatic lipase (triacylglycerol lipase, E.C.3.

TiO₂ beads and TiO₂-chitosan beads for urease immobilization.

The aim of the present study is to synthesize TiO2 beads for urease immobilization. Two different strategies were used to immobilize the urease on TiO2 beads. In the first method (A), urease enzyme was immobilized onto TiO2 beads by adsorption and then crosslinking.