Publications by authors named "Ilya S Demyanchuk"
Ac-DEVD-CHO (caspase-3/DEVDase inhibitor) suppresses self-incompatibility-induced programmed cell death in the pollen tubes of petunia (Petunia hybrida E. Vilm.).
Ekaterina Vladimirovna Zakharova Ilya Sergeevich Demyanchuk Denis Sergeevich Sobolev Yaroslav Yurievich Golivanov Ekaterina Nikolaevna Baranova
Cell Death Discov
January 2024
Programmed cell death (PCD) is relevant to many aspects in the growth and development of a plant organism. In their reproduction, many flowering plant species possess self-incompatibility (SI), that is an intraspecific reproductive barrier, which is a genetic mechanism ensuring the avoidance of inbreeding depression by preventing self-pollination. This phenomenon enhances intraspecific variation; however, SI is rather a hindrance for some fruit plant species (such as plum, cherry, and peer trees) rather than an advantage in farming.
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- Researchers are developing new strategies to improve the production and purification of recombinant proteins in plants by optimizing gene codon composition and exploring regulatory sequences.
- A case study on interferon-αA demonstrated that using a thermostable protein stabilizer (lichenase) significantly enhances the yield of recombinant proteins without negatively affecting their biological activity.
- The combination of protein stabilization and methods for purifying fusion proteins leads to efficient and cost-effective approaches for producing valuable proteins in plant systems.