Publications by authors named "Ilya Golovkin"
In terms of the incidence among all tumors, skin cancer is on top, with the most deadly among them being melanoma. The search for new therapeutic agents to combat melanoma is very relevant. In our opinion, antisense oligonucleotides (ASO) aimed at suppressing the genes responsible for their viability in cancer cells give hope for treatment, which makes it possible to eliminate cancer cells near the tumor site both before and after surgery.
View Article and Find Full Text PDFInsects vastly outnumber us in terms of species and total biomass, and are among the most efficient and voracious consumers of plants on the planet. As a result, to preserve crops, one of the primary tasks in agriculture has always been the need to control and reduce the number of insect pests. The current use of chemical insecticides leads to the accumulation of xenobiotics in ecosystems and a decreased number of species in those ecosystems, including insects.
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- The study addresses the ongoing need for affordable and effective localized treatments for rheumatoid arthritis.
- Researchers investigated the effects of Cytos-11, an antisense oligonucleotide, on reducing TNF-α gene expression in a rat model of the disease.
- The treatment with Cytos-11 showed positive results similar to the well-known drug adalimumab (Humira), indicating that antisense technology drugs could be a promising avenue for rheumatoid arthritis therapy.
We obtained two novel draft genomes of type strains with estimated genome sizes of 5.14 Mb for KMM 3526 and 5.16 Mb for KMM 3676.
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