Publications by authors named "Ilse Roebben"

Purpose: To evaluate the diagnostic accuracy of the visual assessment of malignant pleural mesothelioma (MPM) on magnetic resonance (MR) images by using two known visual markers (mediastinal pleural thickness and shrinking of the lung) and a newly introduced one (pleural pointillism).

Materials And Methods: With the approval of the local ethics committee, 100 consecutive patients (mean age, 61.4 years; age range, 18-87 years; 75 men, 25 women) suspected of having MPM pleural abnormalities underwent positron emission tomography/computed tomography and MR imaging, including diffusion-weighted (DW) MR imaging, followed by explorative thoracoscopy or guided biopsy with histopathologic confirmation.

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Introduction: In head and neck squamous cell carcinoma (HNSCC) the ability to anticipate an individual patient's outcome is very valuable. With this study we wanted to assess the prognostic value of pretreatment apparent diffusion coefficient (ADC) in a large patient population and integrate it into a multivariable prognostic model.

Methods: From 2004 to 2010 175 patients with pathology proven HNSCC were included in this study.

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Purpose: To investigate the use of diffusion-weighted (DW) imaging for differentiating benign lesions from malignant pleural disease (MPD) and to retrospectively assess dynamic contrast material-enhanced (DCE) magnetic resonance (MR) imaging acquisitions to find out whether combining these measurements with DW imaging could improve the diagnostic value of DW imaging.

Materials And Methods: This study was approved by the local ethics committee, and all patients provided written informed consent. Thirty-one consecutive patients with pleural abnormalities suspicious for MPD underwent whole-body positron emission tomography (PET)/computed tomography (CT) and thorax MR examinations.

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Purpose: To evaluate the use of semi-quantitative dynamic contrast-enhanced MRI (DCE-MRI) parameters for the detection of prostatic carcinoma in correlation to whole-mount histopathology.

Materials And Methods: Fifty-three patients with biopsy-proven prostate cancer were examined by DCE-MRI at 1.5-T.

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Article Synopsis
  • The study evaluated the effectiveness of diffusion-weighted magnetic resonance imaging (DW-MRI) in distinguishing hepatocellular carcinoma (HCC) from benign lesions in cirrhotic patients, comparing it to traditional dynamic contrast-enhanced MRI.
  • Results showed that while signal intensity ratios differed significantly between malignant and benign lesions for all measured b-values, there was no notable difference in apparent diffusion coefficients.
  • DW-MRI at the b600 value demonstrated higher sensitivity (95.2%) and specificity (82.7%) for detecting malignant lesions versus conventional MRI, making it particularly useful for identifying small HCC tumors under 2 cm.
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