The second week corneal changes in rodents model of streptozotocin-induced diabetes.

Objective: Aim: Installation the changes of the microstructural rearrangement of the layers of the rat cornea at the end of the second week of experimental streptozotocin- induced diabetes.

Patients And Methods: Materials and Methods: The research was conducted on 15 sexually mature, outbred white male rats, weighing 120-130 g. Two groups of animals were used in the work: the first group with developing diabetes (2 weeks after administration of streptozotocin); the second group served as control and received injections of 0.

Influence of maternal rats' hypothyroidism on morpho-functional peculiarities and glycome of progeny skin.

We studied the influence of maternal hypothyroidism on progeny skin morphogenesis by means of histological, histochemical and lectin-histochemical methods. Hypothyroid conditions in rats were achieved by daily food supplementation with antithyroid drug Mercazolil. The experiment was conducted on 10 control and 10 hypothyroid rats, which delivered 70 and 46 offsprings, respectively.

Hydrogen Sulfide Prevents Mesenteric Adipose Tissue Damage, Endothelial Dysfunction, and Redox Imbalance From High Fructose Diet-Induced Injury in Aged Rats.

A high fructose diet (HFD) and advanced age are key factors for the gradual loss of physiological integrity of adipose tissue. Endogenous hydrogen sulfide (HS) has beneficial effects on cytoprotection and redox balance. But its interactive effects on age-related damage of mesenteric vessels and connective and adipose tissues (MA) during HFD which could be the base of the development of effective physiological-based therapeutic strategy are unknown.