Binding Between Cyclohexanohemicucurbit[]urils and Polar Organic Guests.

Inherently chiral, barrel-shaped, macrocyclic hosts such as cyclohexanohemicucurbit[]urils (cycHC[]) bind zinc porphyrins and trifluoroacetic acid externally in halogenated solvents. In the current study, we tested a set of eighteen organic guests with various functional groups and polarity, namely, thiophenols, phenols, and carboxylic and sulfonic acids, to identify a preference toward hydrogen bond-donating molecules for homologous cycHC[6] and cycHC[8]. Guests were characterized by Hirshfeld partial charges on acidic hydrogens and their binding by H and F NMR titrations.

From Work Ability Research to Implementation.

Work ability research started in Finland in the 1990s due to the challenges of work force aging. The employment rates of older workers (55+) were below 40% and early retirement and work disability rates were rather common in many European countries. The work ability concept and methods were developed and broad international research activities started in the 1990s.

Trajectories of mobility limitations over 24 years and their characterization by shift work and leisure-time physical activity in midlife.

Background: We aimed to investigate trajectories of mobility limitations (MLs) over a period of 24 years. In addition, we aimed to study how shift work and leisure-time physical activity (LTPA) in midlife predict assignment to MLs trajectories separately for those retired on statutory pensions (SPs) and on disability pensions (DPs).

Methods: Subjects who responded MLs questionnaires (1985-2009, N = 3048) in Finnish Longitudinal Study on Aging Municipal Employees were included in this prospective cohort study.

Multisite musculoskeletal pain trajectories from midlife to old age: a 28-year follow-up of municipal employees.

Objectives: We studied the developmental trajectories of multisite musculoskeletal pain (MSP) to learn whether pain in midlife persists to old age, and whether pain trajectories associate with midlife work or lifestyle exposures or retirement from work.

Methods: Municipal employees aged 44-58 years were studied in 1981 (n=6257) with follow-ups in 1985, 1992, 1997 and 2009. Pain in the neck, low back, and upper and lower limbs was assessed in each survey.

Work-Related Biomechanical Exposure and Job Strain as Separate and Joint Predictors of Musculoskeletal Diseases: A 28-Year Prospective Follow-up Study.

We investigated how work-related biomechanical exposure and job strain in midlife separately and jointly predicted back and degenerative musculoskeletal diseases (MSDs). A total of 6,257 employees participated in the Finnish Longitudinal Study on Aging Municipal Employees (FLAME) in 1981 and were followed up for 28 years. Risk ratios and the relative excessive risk due to interaction and 95% confidence intervals were modeled for separate and joint prediction estimates, respectively.

Work-related biomechanical exposure and job strain in midlife separately and jointly predict disability after 28 years: a Finnish longitudinal study.

Objectives We investigated whether the extent of biomechanical exposures and job strain in midlife separately and jointly predict disability in old age. Methods Participants of the Finnish Longitudinal Study on Aging Municipal Employees (FLAME) in 1981 (aged 44-58 years) responded to disability questionnaires in 2009 (1850 women and 1082 men). Difficulties in performing five activities of daily living (ADL) and seven instrumental ADL (IADL) were used to assess severity of disability (score range: 0-12, 0=no disability).

Midlife job profiles and disabilities in later life: a 28-year follow-up of municipal employees in Finland.

Purpose: Occupations during adult life may have long-term effects and subsequently increase the risk of disability in old age. We investigated the associations between job profile groups in midlife and disability in old age for women and men.

Methods: This prospective 28-year follow-up study (1981-2009) examined 2998 municipal employees (1892 women and 1106 men) aged 44-58 years at baseline.

Midlife work ability and mobility limitation in old age among non-disability and disability retirees--a prospective study.

Background: Little is known about the wellbeing and mobility limitation of older disability retirees. Personal and environmental factors, such as time spent in working life, may either exacerbate or mitigate the onset of mobility limitation in general population. We aimed to study perceived midlife work ability as a determinant of self-reported mobility limitation in old age among municipal employees who transitioned into non-disability and disability retirement.

Examining the factorial structure, measurement invariance and convergent and discriminant validity of a novel self-report measure of work ability: work ability--personal radar.

Unlabelled: For identification of groups and domains for work ability promotion, brief self-report measure, work ability - personal radar (WA-PR), based on the 'the house of work ability' model is presented and psychometrically evaluated in the structural equation framework using data from technological sector (N = 3754). The house model had acceptable fit to the data. In addition, factor loadings in the model were invariant across groups, demonstrating metric invariance of the WA-PR.

Type of retirement as a determinant of pre- and post-retirement hospital in-patient care use: a prospective study.

Background: We examined prospectively the use of all-cause hospital in-patient care among public sector employees by using a 3-year pre- and post-retirement study window.

Methods: A total of 5269 participants of the Finnish Longitudinal Study of Municipal Employees had retired during January 1984 and July 2000. They had register-based data on retirement (non-disability retirement n = 3411, men 40%, and diagnose-specific disability retirement n = 1858, men 50%) and all-cause hospital in-patient admissions and discharges.

Work-related stress in midlife is associated with higher number of mobility limitation in older age-results from the FLAME study.

The aim of this study is to investigate whether work-related stress symptoms in midlife are associated with a number of mobility limitations during three decades from midlife to late life. Data for the study come from the Finnish Longitudinal Study of Municipal Employees (FLAME). The study includes a total of 5429 public sector employees aged 44-58 years at baseline who had information available on work-related stress symptoms in 1981 and 1985 and mobility limitation score during the subsequent 28-year follow-up.

Inverse effects of midlife occupational and leisure time physical activity on mobility limitation in old age--a 28-year prospective follow-up study.

Objectives: To evaluate in a sample of initially middle-aged municipal employees whether leisure time (LPA) or occupational physical activity (OPA) was associated with mobility limitation (ML) in old age.

Design: Prospective population-based follow-up.

Setting: Municipalities in Finland.

Job strain in the public sector and hospital in-patient care use in old age: a 28-year prospective follow-up.

Background: high job strain increases the risk of health decline, but little is known about the specific consequences and long-term effects of job strain on old age health.

Objectives: purpose was to investigate whether physical and mental job strain in midlife was associated with hospital care use in old age.

Methods: study population included 5,625 Finnish public sector employees aged 44-58 years who worked in blue- and white-collar professions in 1981.

Perceived stress symptoms in midlife predict disability in old age: a 28-year prospective cohort study.

Background: Stress has damaging effects on individual's health. However, information about the long-term consequences of mental stress is scarce.

Methods: This 28-year prospective cohort study examined on the associations between midlife stress and old age disability among 2,994 Finnish municipal professionals aged 44-58 years at baseline.

Job strain among blue-collar and white-collar employees as a determinant of total mortality: a 28-year population-based follow-up.

Objectives: To investigate the effect of job demand, job control and job strain on total mortality among white-collar and blue-collar employees working in the public sector.

Design: 28-year prospective population-based follow-up.

Setting: Several municipals in Finland.

Work ability as a determinant of old age disability severity: evidence from the 28-year Finnish Longitudinal Study on Municipal Employees.

Background And Aims: Lower occupational class correlates with a higher disability risk later in life. However, it is not clear whether the demands made by mental and physical work relative to individual resources in midlife predict well-being in old age. This study investigated prospectively whether work ability in midlife predicts disability severity in activities of everyday living in old age.

Strategic wellness management in Finland: The first national survey of the management of employee well-being.

Objectives: To examine the scope of strategic wellness management (SWM) in Finland. To measure management of wellness a strategic wellness management index (SWMI) was developed.

Methods: On the basis of the developed SWM model an Internet questionnaire was conducted for randomly selected employers representing seven business areas and three size categories.

Work strain in midlife and 28-year work ability trajectories.

Objectives: We investigated the 28-year development trajectories of work ability among initially middle-aged male and female municipal employees and the association of perceived mental and physical work strain in midlife by work ability trajectory groups.

Methods: The baseline data of the Finnish longitudinal study of municipal employees (FLAME) were collected in 1981 (N=6257) with follow-ups in 1985, 1992, 1997, and 2009. Work ability was assessed in all the waves as present perceived work ability relative to lifetime best.

Work ability in midlife as a predictor of mortality and disability in later life: a 28-year prospective follow-up study.

Background: Poor work ability correlates with increased morbidity and early retirement from the workforce, but the association in old age is not known. We investigated work ability in midlife among white-collar and blue-collar employees as a predictor of mortality and disability 28 years later.

Methods: A total of 5971 occupationally active people aged 44-58 years participated in the Finnish Longitudinal Study of Municipal Employees (FLAME) in 1981.

Work ability and musculoskeletal disorders among workers from a public health institution.

Objective: The study investigated the associations between diagnosed musculoskeletal disorders (MSD), work ability and demographics, work and lifestyle characteristics in a public health institution with a variety of occupations.

Methods: A cross-sectional study was carried out in a public health institution in Brazil. The subjects (n = 168) aged 20-69 answered a questionnaire on demographics, work, lifestyle characteristics and the work ability index.

Evaluating work ability and quality of life for clinical nurses in Taiwan.

This study investigated the work ability and its relationship with quality of life for the clinical nurses in Taiwan. The survey was of 1534 nursing professionals from 8 different hospitals. Work ability of nursing professionals varied by age, work experience, working departments and hospital types.

Work ability of workers in different age groups in a public health institution in Brazil.

Objectives: The aim of this study was to determine the associations between demographics, work, lifestyle, housework, and the work ability of workers.

Methods: Employees between the ages of 20 and 69 (N = 651), employed at a Brazilian public institution, responded to a questionnaire on demographics, work, lifestyle characteristics, and work ability.

Results: Work ability decreased significantly with age among the women.

Towards a longer and better working life: a challenge of work force ageing.

The aim of this overview is to describe the background of work force ageing and its consequences in the society, to introduce concepts for the solutions, to emphasize the actions needed, to point out the new challenges for occupational health, to review the targets of work life improvements, and to highlight the new innovations needed. Work life must be lengthened for the sake of society. Early retirement and low employment rates of 55-64-years old employees make the dependency ratios an increasingly heavy burden.