Publications by authors named "Ilkyu Park"

Epidemiological evidence suggests that fruit and vegetable intake significantly positively affects cardiovascular health. Since vegetable juice is more accessible than raw vegetables, it attracts attention as a health functional food for circulatory diseases. Therefore, this study measured blood lipids, antioxidants, blood circulation indicators, and changes in the microbiome to confirm the effect of organic vegetable mixed juice (OVJ) on improving blood circulation.

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Hepatocellular carcinoma (HCC) is one of the leading causes of cancer death worldwide, and classifying the developmental stages of HCC can help with early prognosis and treatment. This study aimed to investigate diagnostic and prognostic molecular signatures underlying the progression of HCC, including tumor initiation and growth, and to classify its developmental stages based on gene expression levels. We integrated data from two cancer systems, including 78 patients with Edmondson-Steiner (ES) grade and 417 patients with TNM stage cancer.

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To address the increasing demand for multicolor light-emitting diodes (LEDs), a monolithic multicolor LED with a simple process and high reliability is desirable. In this study, organic-inorganic hybrid LEDs with violet and green wavelengths were fabricated by depositing CsPbBr perovskite green quantum dots (QDs) as the light-converting material on InGaN-based violet LEDs. As the injection current was increased, the total electroluminescence (EL) intensities of the hybrid LEDs increased, whereas the light-converted green emission efficiency of the CsPbBr QDs decreased.

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The recent application of the internet of things demands the ubiquitous utilization of data and electrical power. Even with the development of a wide variety of energy-harvesting technologies, few studies have reported a device transporting electrical energy and data simultaneously. This paper reports an electrostatic induction nanogenerator (ESING) consisting of a one-dimensional metastructure that can modulate the output voltage based on the resonance of ultrasound waves to transmit energy and data simultaneously.

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Aims: The timely diagnosis of different stages in NAFLD is crucial for disease treatment and reversal. We used hepatocellular ballooning to determine different NAFLD stages.

Main Methods: We analyzed differentially expressed genes (DEGs) in 78 patients with NAFLD and in healthy controls from previously published RNA-seq data.

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Article Synopsis
  • Inflammatory bowel disease (IBD) includes chronic conditions like ulcerative colitis and Crohn's disease, with a focus on understanding terminal-ileal and colonic types at a molecular level for better clinical management.
  • The study analyzed gene expression in 23 pediatric Crohn's disease patients and 25 healthy controls, utilizing statistical models to pinpoint genes linked to specific disease locations.
  • A total of 550 differentially expressed genes were identified, with 33 showing strong potential as biomarkers for distinguishing between terminal-ileal and colonic Crohn's disease, validated through further testing in independent cohorts.
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Papillary renal cell carcinoma (pRCC), which accounts for 10-15% of renal cell carcinomas, is the second most frequent renal cell carcinoma. pRCC patient classification is difficult because of disease heterogeneity, histologic subtypes, and variations in both disease progression and patient outcomes. Nevertheless, symptom-based patient classification is indispensable in deciding treatment options.

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Article Synopsis
  • Sexual size dimorphism (SSD) in olive flounders shows that females have greater bone mass than males, but the mechanisms and timing behind this difference are still debated.* -
  • A study identified 4,784 genes with sex-biased expression in adult olive flounders, indicating that while males have genes related to inhibiting cell growth, females have genes promoting growth and development.* -
  • Five specific genes related to skeletal development were highlighted, suggesting they play a key role in SSD, which could help improve aquaculture practices by optimizing fish growth and reducing costs.*
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Triboelectric nanogenerators (TENGs) have emerged as a next-generation sustainable power source for Internet of Things technology. Polyvinylidene fluoride (PVDF) nanofibers (NFs) have been investigated widely to enhance the TENG performance by controlling their polarity; however, controlling the surface morphology of the PVDF NFs has rarely been studied. Here, surface-roughened, churros-like PVDF NFs were fabricated by controlling the solvent evaporation kinetics.

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Visible-blind ultraviolet (UV) photodetectors have received a great deal of attention for realizing Internet of Things technologies as well as for monitoring the level of UV exposure to humans. Realizing next-generation flexible and visible-blind UV photodetectors requires development of new functional material systems with easy fabrication, selectively strong UV light absorption, environmental friendliness, and high stability regardless of ambient conditions. Herein, flexible visible-blind UV photodetectors are successfully fabricated on the basis of two-dimensional ZnAl-layered double hydroxide (LDH) nanosheets with scroll structures grown on flexible substrates.

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Atomically thin transition metal dichalcogenides (TMDs) have recently attracted great attention since the unique and fascinating physical properties have been found in various TMDs, implying potential applications in next-generation devices. The progress towards developing new functional and high-performance devices based on TMDs, however, is limited by the difficulty in producing large-area monolayer TMDs due to a lack of knowledge of the growth processes of monolayer TMDs. In this work, we have investigated the growth processes of monolayer WS2 crystals using a thermal chemical vapor deposition method, in which the growth conditions were adjusted in a systematic manner.

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Background: Purulent musculoskeletal infections often require surgical debridement and drainage. However, when the infection is extensive or involving multiple layers of tissues, maintaining drainage of the involved spaces can be difficult, even with the application of vacuum-assisted closure (VAC) therapy. Wide exposure and aggressive debridement is often required for such cases, which in turn may complicate wound coverage.

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Mechanically robust composite nanofibers (NFs) with enhanced magnetic properties were made from polyvinylidene fluoride (PVDF) and FeO nanoparticles (NPs) by an electrospinning method. At up to 11.3 wt %, FeO NPs were embedded randomly in the PVDF NFs, but when the content exceeded 17 wt %, the NPs aggregated on the NF surfaces.

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We report on the fabrication of ZnO nanorod (NR)-based flexible piezoelectric nanogenerators (PENGs) on carbon paper (CP). Structural investigations indicate that the ZnO NRs grew well along the porous CP surface. Optical investigation shows that the crystal quality of the ZnO NRs on the CP was comparable to that of NRs grown on Si substrate.

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Background: Control of foodborne pathogens is an important issue for the fruit juice industry and ohmic heating treatment has been considered as one of the promising antimicrobial interventions. However, to date, evaluation of the relationship between inactivation of foodborne pathogens and system performance efficiency based on differing soluble solids content of apple juice during ohmic heating treatment has not been well studied. This study aims to investigate effective voltage gradients of an ohmic heating system and corresponding sugar concentrations (°Brix) of apple juice for inactivating major foodborne pathogens (E.

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Flexible piezoelectric nanogenerators (PNGs) based on a composite of ZnO nanorods (NRs) and an array of Si micro-pillars (MPs) are demonstrated by a transfer process. The flexible composite structure was fabricated by hydrothermal growth of ZnO NRs on an electrochemically etched Si MP array with various lengths followed by mechanically delaminating the Si MP arrays from the Si substrate after embedding them in a polydimethylsiloxane matrix. Because the Si MP arrays act as a supporter to connect the ZnO NRs electrically and mechanically, verified by capacitance measurement, the output voltage from the flexible PNGs increased systematically with the increased density ZnO NRs depending on the length of the Si MPs.

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Background: A contralateral normal hip joint has been often used as a reference standard in preoperative planning and intraoperative assessment of hip arthroplasty, with the assumption that bilateral hip joint geometries have no significant differences. However, one previous study using analog measurements on hardcopy films reported significant bilateral variation in hip joint geometry. We therefore investigated the level of agreement between the right and left hips for each measurement and determined index values and the range of normal bilateral variations.

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We demonstrate the enhancement of output power from a ZnO nanorod (NR)-based piezoelectric nanogenerator by using Si microhole (Si-μH) arrays. The depth-controlled Si-μH arrays were fabricated by using the deep reactive ion etching method. The ZnO NRs were grown along the Si-μH surface, in holes deeper than 20 μm.

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Background: The authors developed a novel treatment based on the topical application of a silicone gel sheet containing verapamil microparticles. The ability of these silicone gel sheets to inhibit hypertrophic scar in a rabbit ear wound model was examined.

Methods: Ten New Zealand White rabbits with a total of 80 wounds in both ears were used in this study.

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Enhanced output power from a ZnO nanorod (NR)-based piezoelectric nanogenerator (PNG) is demonstrated by forming a heterojunction with Si micropillar (MP) array. The length of the SiMP array, which was fabricated by electrochemical etching, was increased systematically from 5 to 20 μm by controlling the etching time. Our structural and optical investigations showed that the ZnO NRs were grown hierarchically on the SiMPs, and their crystalline quality was similar regardless of the length of the underlying SiMPs.

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We demonstrate the fabrication of a graphene/ZnO nanorod (NR) hybrid structure by mechanical exfoliation of ZnO NRs grown on a graphite substrate. We confirmed the existence of graphene sheets on the hybrid structure by analyzing the Raman spectra and current-voltage (I-V) characteristics. The Raman spectra of the exfoliated graphene/ZnO NR hybrid structure show G and 2D band peaks that are shifted to lower wavenumbers, indicating that the exfoliated graphene layer exists under a significant amount of strain.

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Background: A few studies about lymphoscintigraphy in breast cancer patients have reported a correlation between decreased sentinel lymph node (LN) uptake and increased risk of axillary involvement with the hypothesis of blocked lymphatic passage of radiotracers by metastatic burden. This study is designed to investigate whether the visible internal mammary LN of lymphoscintigraphy (IM-LPS) is related to axillary LN metastasis, rather than identifying sentinel LN in the internal mammary area.

Methods: We retrospectively reviewed medical records of 401 breast cancer patients who underwent sentinel lymphoscintigraphy using Tc-99m phytate and subsequent axillary LN dissection.

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We demonstrate the fabrication of solution based low temperature-processed p-type ZnO NRs doped with phosphorous by using a spin-on-dopant method coupled with a hydrothermal process. We confirmed the incorporation of phosphorous dopants into a ZnO crystal by analyzing SIMS profiles, together with the evolution of the photoluminescence spectra. It is further revealed that the electrical properties of the p-type ZnO/n-type Si heterojunction diode exhibited good rectifying behavior, confirming that p-type ZnO NRs were successfully formed.

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In this study, we fabricated and characterized three dimensional (3D) silicon (Si)/zinc oxide (ZnO) hybrid subwavelength structures to investigate their antireflective properties. Si nanorods (SiNRs) were fabricated by electrochemical etching, and subsequentially we grew ZnO NRs on SiNR as templates by using hydrothermal synthesis. The morphological and optical properties of hybrid Si/ZnO subwavelength structures were investigated by scanning electron microscopy (SEM) and ultra violet-visible-near infrared (UV-VIS-NIR) spectrophotometer, respectively.

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