Publications by authors named "Ilke Yıldırım"
Characteristics of childhood anaphylaxis in different age groups.
Allergol Immunopathol (Madr)
September 2024
Article Synopsis
- Anaphylaxis is a serious allergic reaction often triggered by food or drugs, with its onset being rapid and potentially life-threatening.
- A study of 177 pediatric patients from a tertiary care center revealed that food allergies, especially egg allergies, were the most frequent triggers, with skin reactions being the most commonly observed symptoms.
- The research indicated that younger children are more likely to experience food-induced anaphylaxis, while older adolescents showed an increasing trend in drug-induced cases, suggesting that the nature and severity of anaphylaxis changes with age.
Article Synopsis
- Primary immune deficiencies (PIDs) are rare genetic disorders that result in weakened immune systems, leading to frequent infections and a higher risk of cancer and lymphoproliferative disorders.
- In a study of 550 pediatric patients with PID, 17 (3.0%) were found to have malignancies or benign lymphoproliferations, with immune dysregulatory diseases being the most common cause.
- Lymphoma was the most frequently observed malignancy, and Epstein-Barr virus was identified as the most common viral agent involved, emphasizing the need for early diagnosis and ongoing care for affected patients.
Unlabelled: Introduction-Objective: X-linked agammaglobulinemia (XLA) is a primary immunodeficiency disease predominantly with antibody deficiency and characterized by recurrent pyogenic infections, absence of B cells and agammaglobulinemia. In this study, it is aimed to review the demographic data of our XLA patients and examine the frequency of severe bacterial and mild infections and benefits of immunoglobulin replacement therapies to reduce the rate of infections. In addition, correlations between genotypic results and clinical and laboratory findings were searched.
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