Stable hemiaminals from axially chiral pyridine compounds.

In this study, we have synthesized a series of 3-(pyridin-2-yl)-2-(pyridin-2-ylimino)thiazolidin-4-ol derivatives regioselectively from 2-iminothiazolidin-4-ones using LiAlH at room temperature. Due to the presence of the restricted rotation around the N3-C single bond, the formation of M/P isomers was observed. The OH group of the hemiaminal was found to orient itself on the same side with pyridyl nitrogen during this restricted rotation to form an intramolecular hydrogen bond, which was demonstrated by the computational DFT study.

FakeCatcher: Detection of Synthetic Portrait Videos using Biological Signals.

The recent proliferation of fake portrait videos poses direct threats on society, law, and privacy [1]. Believing the fake video of a politician, distributing fake pornographic content of celebrities, fabricating impersonated fake videos as evidence in courts are just a few real world consequences of deep fakes. We present a novel approach to detect synthetic content in portrait videos, as a preventive solution for the emerging threat of deep fakes.