Pulmonary vein isolation (PVI) using a novel endoscopic ablation system (EAS) shows promising results for treating drug-refractory atrial fibrillation (AF) with 60% of patients remaining free from symptoms after one year.
A study involving 40 patients revealed that 99% of targeted pulmonary veins were successfully isolated, and some patients experienced AF recurrence due to reconnection of isolated veins.
More extensive research with larger patient groups and longer follow-up is needed to fully assess the safety and effectiveness of EAS for AF treatment.
The study aimed to evaluate the occurrence and severity of esophageal thermal lesions (ETLs) resulting from two different methods of pulmonary vein isolation (PVI) in patients with atrial fibrillation.
In a comparison of an endoscopic ablation system (EAS) and radio frequency current (RFC), the EAS group had a higher percentage of patients with thermal lesions (18%) compared to the RFC group (15%), with a notable presence of ulcerations in the EAS group.
Although all detected thermal lesions healed within a few days, the findings suggest that the EAS method may produce more serious ETLs than the RFC method, warranting further research.
CPVI is effective for restoring sinus rhythm (SR) in 43.2% of long-standing persistent AF patients, but often multiple procedures are necessary.
205 patients with long-standing persistent AF underwent CPVI followed by additional techniques if needed, with 67.8% achieving SR after an average of 1.7 procedures.
The study highlights the need for caution due to risks like inadvertent left atrial appendage isolation during additional ablation strategies.
High-intensity focused ultrasound (HIFU) via a balloon catheter is a new method for treating paroxysmal atrial fibrillation (PAF), but its long-term effectiveness is still uncertain.
In a study of 32 patients, HIFU was able to isolate 87% of targeted pulmonary veins, and 56% of patients remained free of AF after a single procedure during a follow-up of about 1400 days.
Despite promising success rates comparable to traditional methods, significant complications from HIFU have caused its clinical use to be suspended.