[The study of characteristics of overdose among users of opioid drug injections].

Overdose is a serious problem as for people addicted to opioid drug injections (ODI) as well as for the community in general. To study characteristics of overdose, authors examined 60 ODI users and analyzed 27 overdose death cases. It has been shown that overdose is rather common among ODI users.

[The questionnaire "alcohol anosognosia" is a new tool for assessment of anosognosia in patients with alcohol dependence].

The aim of this study was to develop and validate a patient-rated questionnaire for the complex express-assessment of alcohol anosognosia. The questionnaire was tested in 106 inpatients diagnosed with alcohol dependence (ICD-10, item F10.2).

[Epidemiology, medical and social features of the addiction to beer and strong alcogol].

The comparative study of the addiction to beer and hard liquor was carried out. Despite of the dramatic increase in the beer consumption in the Russian Federation between 1999 and 2009, the incidence and prevalence of alcohol dependence and alcohol psychoses had decreased. The analysis of preference in alcohol consumption revealed that 90.

[Changes in the hemato-encephalic barrier in experimental liver cirrhosis].

Experiments on 30 Wistar female rats with tetrachloromethane-induced cirrhosis of the liver revealed structural changes in the hematoencephalic barrier presenting as peri- and endocapillary changes and changes in vascular peduncles of astrocytes shown by light and electron microscopy. Hematoencephalic barrier destabilization is conducive to penetration of cerebrotoxins and other metabolic toxins, this explaining the development of hepatic encephalopathy.