Publications by authors named "Iliana Nelly Chavez-Sanchez"
Article Synopsis
- - Cutis laxa is a rare connective tissue disorder that leads to premature aging due to abnormal elastic fibers in the skin; it can be inherited or acquired, with acquired cases being less common and poorly understood.
- - A case study involved a 30-year-old man with type I acquired cutis laxa, showing widespread symptoms affecting kidney, lungs, and digestive system, alongside skin abnormalities confirmed through histological analysis.
- - Treatment included immunosuppressive medications like prednisone, cyclophosphamide, and rituximab, which successfully reduced proteinuria and slowed lung damage, while ruling out other potential autoimmune, infectious, and cancer-related causes.
Background: RS3PE (remitting seronegative symmetrical synovitis with edema and pitting) is a rare entity of unknown etiology that has been related to genetic predisposition due to the presence of HLA-A2 in 50% of cases and less frequently HLA-B7. Its pathogenesis is unknown, but it has been related to growth factors, and some mediators (TNF, IL-6). It is common in elderly people and the course of this illness presents with acute symmetrical polyarthritis, accompanied by edema in hands and feet.
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