Publications by authors named "Ilenia Meloni"

Article Synopsis
  • Fundus images help assess retinal blood vessels non-invasively, allowing researchers to extract 17 different vascular characteristics from over 130,000 images of UK Biobank subjects.
  • Genetic studies reveal that the heritability of these vascular traits ranges from 5% to 25%, and there are distinct genetic links among the traits, indicating different biological mechanisms at play.
  • The research identifies specific vascular features linked to health issues like heart attack and suggests that factors like blood pressure and body mass index may influence retinal vessel shapes.
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Article Synopsis
  • * The study analyzed 5211 OCT scans from 344 eyes of 255 patients with CSCR, identifying 178 recurrent and 109 non-recurrent cases, using advanced AI techniques to extract relevant parameters.
  • * Nine predictive biomarkers for CSCR recurrence were found, including age, various fluid types, and specific retinal layer thicknesses, which could enhance automatic detection and improve clinical outcomes in the future.
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In clinical research, the analysis of patient cohorts is a widely employed method for investigating relevant healthcare questions. The ability to automatically extract large-scale patient cohorts from hospital systems is vital in order to unlock the potential of real-world clinical data, and answer pivotal medical questions through retrospective research studies. However, existing medical data is often dispersed across various systems and databases, preventing a systematic approach to access and interoperability.

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Invertebrates such as Drosophila melanogaster have proven to be a valuable model organism for studies of the nervous system. In order to control neuronal activity, optogenetics has evolved as a powerful technique enabling non-invasive stimulation using light. This requires light sources that can deliver patterns of light with high temporal and spatial precision.

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