Publications by authors named "Ilenia Azzena"

Following the increased mass mortality of populations in the Mediterranean, reliable protocols for the transport, maintenance, and controlled reproduction of this highly endangered species were drawn up within the European Life Pinna project. To test these protocols, the large Pinnidae , which shares similar habits to , has been used. In December 2022, a transport trial of nine specimens of from Trieste (NE Italy) to Camogli (NW Italy) was carried out.

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Background: Climate change significantly influences the distribution and severity of tropical diseases. Rising temperatures, changing precipitation patterns, and extreme weather events are transforming the habitats of vectors like mosquitoes and ticks, promoting their proliferation and geographic spread. These changes have facilitated the resurgence of diseases such as malaria, dengue, and chikungunya fever in previously unaffected areas, including parts of Europe and Italy.

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The family includes a number of negative RNA viruses known for their wide host range and significant zoonotic potential. In recent years, there has been a surge in the identification of emerging zoonotic paramyxoviruses, particularly those hosted by bat species, which serve as key reservoirs. Among these, the genera Henipavirus and Pararubulavirus are of particular concern.

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Article Synopsis
  • HPV is a common virus linked to cervical and other cancers, and the development of HPV vaccines has significantly decreased disease rates worldwide.
  • Despite their effectiveness, challenges such as low vaccination in lower-income countries, vaccine hesitancy, and healthcare access disparities hinder global immunization efforts.
  • This review discusses the mechanisms, safety, and real-world efficacy of HPV vaccines, current distribution challenges, public health policies, and future innovations in HPV vaccination strategies.
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  • Viral hepatitis is a global health issue, characterized by complex interactions between hepatitis viruses and human liver cells, affecting disease progression and severity.
  • The paper focuses on how different hepatitis viruses (B, C, D, and E) enter liver cells, replicate, evade the immune system, and cause liver damage, as well as the body's immune responses to these infections.
  • It emphasizes the importance of understanding individual factors influencing susceptibility to viral hepatitis and highlights new findings on chronic infection mechanisms, aiming to inform better treatment strategies.
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From 1 January 2022 to 31 May 2024, the World Health Organization (WHO) reported 97,745 laboratory-confirmed Mpox cases, including 203 deaths, across 116 countries. Despite a 2.3% decrease in new cases in May 2024 compared to April 2024, significant regional variations persist.

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  • The Atlantic blue crab is a big problem in the Mediterranean Sea because it's an invasive species, hurting nature and people's activities.
  • It originally comes from the western Atlantic and has been spreading to European waters since the early 1900s.
  • Researchers studied the crab's genetic makeup using many samples, finding two closely related groups and low genetic diversity in the Mediterranean, except for some differences in Turkey.
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The COVID-19 pandemic underscored the critical importance of vaccination to global health security and highlighted the potential of digital health solutions to improve immunization strategies. This article explores integrating digital health technologies with immunization programs to improve coverage, monitoring, and public health outcomes. It examines the current landscape of digital tools used in immunization initiatives, such as mobile health apps, electronic health records, and data analytics platforms.

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Orf virus (ORFV) belongs to the genus Parapoxvirus (Poxviridae family). It is the causative agent of contagious ecthyma (CE) that is an economically detrimental disease affecting small ruminants globally. Contagious ecthyma outbreaks are usually reported in intensive breeding of sheep and goats but they have also been reported in wildlife species.

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, commonly known as the noble pen shell, is a marine bivalve endemic to the Mediterranean Sea. Unfortunately, due to a multifactorial disease that began affecting its populations in 2016, the species is currently facing the threat of extinction. To gain insights into the evolutionary history of before the mass mortality event (MME), and to obtain a comprehensive understanding of how evolutionary processes led to the adaptation of the species into the Mediterranean Sea, phylogenetic and phylogeographic analyses were carried out.

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  • The XBB.1.16 variant of SARS-CoV-2, derived from the XBB lineage, possesses additional spike mutations that may help it evade the immune response effectively compared to other viruses.
  • * Despite these mutations, XBB.1.16 shows a slower evolutionary rate and limited diversification, indicating it is not as dangerous as other rapidly evolving variants.
  • * Ongoing genomic monitoring is crucial for tracking the evolution of the XBB.1.16 variant and understanding its impact in relation to other circulating lineages.
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  • The EG.5 lineage of SARS-CoV-2 is a new variant that is being closely monitored due to an increase in its prevalence, but concerns about its threat level are being evaluated.
  • Current genetic and structural data suggest that EG.5 does not show a significant ability for widespread transmission or increase in population size, with its evolutionary rate remaining relatively low.
  • These findings highlight the importance of continuous genome-based monitoring to stay prepared and informed about the situation as it develops.
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Recombination events are very common and represent one of the primary drivers of RNA virus evolution. The XBF SARS-CoV-2 lineage is one of the most recently generated recombinants during the COVID-19 pandemic. It is a recombinant of BA.

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Since the beginning of the pandemic, the generation of new variants periodically recurs. The XBB.1.

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The SARS-CoV-2 BF.7 variant represents one of the most recent subvariant under monitoring. At the beginning of the 2023 it caused several concerns especially in Asia because of a resurge in COVID-19 cases.

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Recombination is the main contributor to RNA virus evolution, and SARS-CoV-2 during the pandemic produced several recombinants. The most recent SARS-CoV-2 recombinant is the lineage labeled XBB, also known as Gryphon, which arose from BJ.1 and BM.

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Biological invasions are a major threat to the conservation of biodiversity, as invasive species affect native biota through competition, predation, pathogen introduction, habitat alteration, and hybridisation. The present study focuses on a southern pike population, (Teleostei: Esocidae), that has been introduced outside the species' native range. Using microsatellite markers, this study's objective was to gather baseline genetic information and assess the presence of hybrids between this species and in the introduced population.

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The BQ.1 SARS-CoV-2 variant, also known as Cerberus, is one of the most recent Omicron descendant lineages. Compared to its direct progenitor BA.

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The genus (Blenniidae) comprises freshwater blenny fish that inhabits Mediterranean Sea, Black Sea, and north-east Atlantic areas. Three species were formally described to date: . , and .

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Monkeypox is caused by a sylvatic, double-stranded DNA zoonotic virus. Since 1 January 2022, monkeypox cases have been reported to WHO from 106 Member States across six WHO regions, and as of 2 October 2022, a total of 68,900 confirmed cases, including 25 deaths, occurred. Here, by using a whole genome approach, we perform a genetic and phylodynamic survey of the monkeypox virus Clade IIb B.

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Knowledge of Genetic diversity and its spatial distribution is crucial to improve conservation plans for endangered species. Genetic tools help ensure species' long-term persistence by unraveling connectivity patterns and evolutionary trajectories of populations. Here, microsatellite genotypes of individuals from populations of are used to assess the effect of sample size on metrics of within-and between-population genetic diversity by combining empirical and simulated data.

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Orf virus (ORFV) is distributed worldwide and is the causative agent of contagious ecthyma that mainly occurs in sheep and goats. This disease was reported for the first time at the end of 18th century in Europe but very little is currently known about the temporal and geographic origins of this virus. In the present study, the use of new Italian whole genomes allowed for better inference on the evolutionary history of ORFV.

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Article Synopsis
  • * Researchers collected 38 specimens from central Vietnam and used mitochondrial gene analysis (COI) to correctly identify the species and investigate genetic variation across different regions.
  • * Findings revealed that the Vietnamese specimens belonged to a specific species, indicating a possible founder effect in Southeast Asia, while also highlighting the need for future studies to include more genetic sequences from various countries for a comprehensive understanding of global genetic variation.
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