Publications by authors named "Ilene K Brill"

Article Synopsis
  • - The study highlights the rising burden of HPV-related cancers in Indonesia, emphasizing the need for effective cervical cancer screening among HIV-positive women, particularly in Bali.
  • - Researchers conducted a pre- and post-education program with 200 HIV+ women, revealing that 54% had abnormal Pap results and a high prevalence of high-risk HPV types, while education significantly improved knowledge about HPV and cervical cancer.
  • - The findings indicate that a large percentage of women at risk could have benefited from the 9-valent HPV vaccine, suggesting that timely vaccination and education could help prevent cervical cancer in this vulnerable group.
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Article Synopsis
  • The study investigates how race/ethnicity and HIV status affect hypertension outcomes, focusing on awareness, treatment, and control among women.
  • The research involved cisgender women living with HIV and matched women without HIV, evaluating data from the Women's Interagency HIV Study between 2013 and 2019.
  • Results indicate that while non-Hispanic black women quickly recognized their hypertension, they took longer to manage it, whereas women with HIV were quicker to receive treatment compared to those without HIV.
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BACKGROUND: Smoking cessation reduces mortality and morbidity. However, the extent and rapidity at which cessation reduces contemporary death rates from smoking-related illnesses remain uncertain. METHODS: We pooled current or former versus never cigarette smoker hazard ratios from four national cohorts with linkage to death registries in the United States, United Kingdom, Norway, and Canada among adults 20 to 79 years of age from 1974 to 2018.

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Article Synopsis
  • The study investigates the prevalence and management of hypertension among women living with HIV, focusing on differences across race/ethnicity.
  • About 56% of the 712 women studied had hypertension, with a notable 83% awareness of their condition, and 63% of those treated effectively controlled their blood pressure.
  • Results showed that non-Hispanic Black women had the highest hypertension prevalence, while Hispanic women had the lowest, and women with HIV were more likely to be on antihypertensive medication compared to those without HIV.
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Background And Aims: Adequate dietary intakes of essential micronutrients are critical to prevent insulin resistance (IR)-related diseases. Even though the excess calorie intake linked with obesity is also associated with such diseases, no previous studies evaluated the importance of meeting the Dietary Reference Intake (DRI) of micronutrients in relation to calorie intake in those at risk for developing IR.

Methods And Results: We evaluated the relationship between the ability or failure to meet the DRI of micronutrients in relation to daily calorie intake in 463 childbearing-age women with a higher prevalence of IR.

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Prior improvements in multiple myeloma (MM) survival were not fully observed in racial and ethnic minorities and older individuals. We hypothesized that improvements in MM management in recent years have reduced these disparities. We used the Surveillance, Epidemiology, and End Results registries to calculate the incidence and relative survival rates (RSRs) of MM in the United States for patients diagnosed from 1993 to 1997 (prethalidomide), 1998 to 2002 (introduction of thalidomide), 2003 to 2007 (bortezomib and lenalidomide), and 2008 to 2012 (upfront bortezomib and lenalidomide, early availability of carfilzomib and pomalidomide).

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Background: Recent advances in the treatment of multiple myeloma (MM) have been associated with improved survival, predominantly among young and white patients. The authors hypothesized that sociodemographic factors, adjusted for race/ethnicity, influence the survival of younger patients with MM.

Methods: Overall survival (OS) data were obtained for individuals included in the Surveillance, Epidemiology, and End Results (SEER-18) program who were diagnosed with MM before the age of 65 years between 2007 and 2012.

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Background: Although urine-based testing for human papillomavirus (HPV) is being explored as a practical approach for cervical cancer screening, whether the results differ by age, race, or indicators of excess body weight or in populations exposed to HPV vaccines has not been documented by previous studies. The purpose of this study was to determine the accuracy of urinary HPV testing for the presence of cervical HPVs and high-grade cervical intraepithelial lesions (grade 2 and 3 cervical intraepithelial neoplasia [CIN]) by the aforementioned population characteristics.

Methods: The study population consisted of 502 women diagnosed with different grades of CIN.

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Purpose: Multiple myeloma (MM) is the most common hematologic malignancy affecting Blacks in the USA, with standardized incidence rates that are twofold to threefold higher than Whites. The rationale for the disparity is unclear.

Methods: Using participants enrolled in the Molecular And Genetic Epidemiology study of myeloma (259 MM cases; 461 controls), we examined the risk of MM associated with family history of cancer, differences by race and among cases, defining clinical features.

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HIV epidemiology informs prevention trial design and program planning. Nine clinical research centers (CRC) in sub-Saharan Africa conducted HIV observational epidemiology studies in populations at risk for HIV infection as part of an HIV prevention and vaccine trial network. Annual HIV incidence ranged from below 2% to above 10% and varied by CRC and risk group, with rates above 5% observed in Zambian men in an HIV-discordant relationship, Ugandan men from Lake Victoria fishing communities, men who have sex with men, and several cohorts of women.

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