Publications by authors named "Ileana Kapic"
Article Synopsis
- The study identifies BBC3 (PUMA) as a crucial protein that regulates germ cell death during ovarian development, impacting the number of primordial follicles formed.
- Disruption of the Bbc3 gene led to a significant increase in germ cell counts in female mice, resulting in a nearly doubled number of primordial follicles by postnatal day 10.
- BBC3 is essential for controlling germ cell death early in development but does not influence germ cell proliferation or the subsequent loss of germ cells during later stages.
