Publications by authors named "Ildze Ventina"
3-Hydroxypropionic acid (3-HP) is a valuable platform chemical that is used as a precursor for several higher value-added chemical products. There is an increased interest in development of cell factories as a means for the synthesis of 3-HP and various other platform chemicals. For more than a decade, concentrated effort has been invested by the scientific community towards developing bio-based approaches for the production of 3-HP using primarily and as production hosts.
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- The text refers to a correction made to a previous article published under the DOI 10.1016/j.crmeth.2021.100062.
- The correction aims to address errors or inaccuracies in the original paper.
- Readers should refer to this correction for accurate information regarding the article's content.
Article Synopsis
- * A new virus-free genome-wide CRISPR screening method is introduced for Chinese hamster ovary cells, utilizing 75,488 gRNAs targeting 15,028 genes and ensuring precise integration of gRNA expression cassettes.
- * The platform successfully identifies 1,980 genes influencing cell proliferation and 77 gene knockouts that enhance survivability under stress from a toxic compound, tunicamycin.
Chemokines and their receptors direct migration and infiltration of immune cells. CCR1 and CCR2 maintain sequence similarity and respond to a number of the same chemokines secreted in lymphoid organs. Expression of CD38 on leukemic cells has been associated with poor clinical outcomes in patients with chronic lymphocytic leukemia (CLL) and is considered as the negative predictor of progression.
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