Publications by authors named "Ilaria Tiravanti"
Myeloid sarcoma (MS) is an extramedullary localization of immature granulocyte cells that can occur in association with acute myeloid leukemia (AML). Gastrointestinal involvement is relatively common in MS, but exclusive colonic localization is a rare occurrence. Here, we report on a 53-year-old male patient affected by AML developing a severe abdominal pain caused by intestinal perforation requiring surgical intervention.
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- The study aimed to determine the prevalence of latent tuberculosis infection (LTBI) in patients with acute leukemia (AL) using the QuantiFERON (QFT)-TB test, as there's no established screening program for such patients in low TB incidence countries.
- A total of 62 AL patients were screened, with 11.3% testing positive for LTBI, and no patients showing symptoms of active TB during the observation period.
- The findings suggest that LTBI may be more prevalent in Italy than previously thought, highlighting the need for TB screening before starting treatment in AL patients, especially as new treatment options become available.
Article Synopsis
- Coagulation disorders, specifically overt disseminated intravascular coagulation (DIC), are common in acute myeloid leukemia (AML) patients and are linked to poorer outcomes.
- The study analyzed 351 newly diagnosed non-promyelocytic AML patients and found that 21% presented with overt DIC, which correlated with advanced age, health issues, and certain genetic markers.
- Patients with DIC experienced significantly higher early mortality rates and overall survival was notably worse compared to those without DIC, emphasizing the need for early detection and intervention.