Publications by authors named "Ilaria Ficarra"
Eur J Med Chem
October 2014
Article Synopsis
- A novel type of squalene conjugates was developed, linking drugs like paclitaxel and camptothecin with a design that allows them to self-assemble in water.
- The compounds are connected by a disulfide linker that enables drug release inside cells, showing effective in vitro performance.
- The paclitaxel-squalene derivative maintains similar effectiveness to free paclitaxel and successfully enters A549 cancer cells, highlighting potential for new squalene-based drug delivery systems.
