Sustained Release of Salicylic Acid for Halting Peri-Implantitis Progression in Healthy and Hyperglycemic Systemic Conditions: A Gottingen Minipig Model.

To develop a peri-implantitis model in a Gottingen minipig and evaluate the effect of local application of salicylic acid poly(anhydride-ester) (SAPAE) on peri-implantitis progression in healthy, metabolic syndrome (MS), and type-2 diabetes mellitus (T2DM) subjects. Eighteen animals were allocated to three groups: (i) control, (ii) MS (diet for obesity induction), and (iii) T2DM (diet plus streptozotocin for T2DM induction). Maxillary and mandible premolars and first molar were extracted.

Ultrathin lithium disilicate and translucent zirconia crowns for posterior teeth: Survival and failure modes.

Purpose: To evaluate the reliability and failure modes of ultrathin (0.5 mm) lithium disilicate, translucent and ultra-translucent zirconia crowns for posterior teeth restorations.

Materials And Methods: Fifty-four mandibular first molar crowns of three ceramic materials: (1) Lithium disilicate (e.

Bone healing around implants placed in subjects with metabolically compromised systemic conditions.

The aim of this study was to evaluate the bone healing of tight-fit implants placed in the maxilla and mandible of subjects compromised with metabolic syndrome (MS) and type-2 Diabetes Mellitus (T2DM). Eighteen Göttingen minipigs were randomly distributed into three groups: (i) control (normal diet), (ii) MS (cafeteria diet for obesity induction), (iii) T2DM (cafeteria diet for obesity induction + Streptozotocin for T2DM induction). Maxillary and mandibular premolars and molar were extracted.

Effects of relative centrifugation force on L-PRF: An in vivo submandibular boney defect regeneration study.

Properties and composition of leukocyte- and platelet-rich fibrin (L-PRF) clots may be largely affected by centrifugation protocols (function of relative centrifugal force [RCF]), which may impact biological potential repair in bone regeneration. The present in vivo study sought to assess the effect of the RCF on the composition of L-PRF clots, as well as to compare the repair potential of L-PRF clots obtained with different RCF protocols in submandibular boney defects using PLGA scaffolds for bone regeneration. Complete blood count and volumetric evaluations were performed on L-PRF clots obtained through centrifugation for 12 min at 200, 400, and 600 RCF-clot centrifugation speeds.

Correlation between 2D and 3D measurements of cement space in CAD-CAM crowns.

Statement Of Problem: Although the 2D analysis of prosthesis cementation space has been popular, its correlation with volumetric comparison (3D data) of cement space is unclear.

Purpose: The purpose of this in vitro study was to evaluate the cement space in computer-aided design and computer-aided manufacturing (CAD-CAM) crowns of different materials and correlate 2D measurements of cement space with their corresponding 3D values (volume of cement space) by using microcomputed tomography (μCT) analysis of regions of interest.

Material And Methods: Ten molar crowns were milled in lithium disilicate (LD), resin nanoceramic (RN), and zirconia (Z) ceramics.

Influence of Abutment Fabrication Method on 3D Fit at the Implant-Abutment Connection.

Purpose: To three-dimensionally evaluate the internal fit at the implant-abutment interface of abutments fabricated with different workflows using a combination of the silicone replica technique and microcomputed tomography (μCT).

Materials And Methods: Thirty abutments were fabricated to restore internal-connection implants and were divided into three groups according to fabrication method: (1) full digital (abutment machined using CAD/CAM system); (2) Ti-Base (prefabricated standard Ti-Base abutments); and (3) UCLA (UCLA-type abutments) (n = 10/group). Linear and volume measurements were performed to assess the internal misfit using a silicone replica of the implant-abutment interface misfit area, which was three-dimensionally reconstructed after μCT.

Three-dimensional misfit between Ti-Base abutments and implants evaluated by replica technique.

Objective: An important factor affecting the biomechanical behavior of implant-supported reconstructions is the implant-abutment misfit. This study evaluated the misfit between Ti-Base abutments and implants by means of polyvinyl siloxane replica technique using microcomputed tomography (μCT).

Methodology: Volumetric and linear (central and marginal) gaps of four Ti-base abutments (n=10/group): (i) Odontofix LTDA (OD), (ii) Singular Implants (SING), (iii) EFF Dental Components (EFF), and (iv) Control Group (S.

Analysis of correlation between optical and microtomography measurements of cementation space in CAD-CAM ceramic crowns.

Statement Of Problem: Identical computer-aided design (CAD) parameters may be used to mill a variety of ceramic materials for computer-aided design and computer-aided manufacture (CAD-CAM) crowns. Whether milled crown spacing matches the designed parameters when more than a single evaluation method is applied is unknown.

Purpose: The purpose of this in vitro study was to correlate the stereomicroscope and the microcomputer tomography (μCT) 2-dimensional analysis of the cementation space with the replica technique in assessing 3 different ceramic materials.

Implant-abutment fit influences the mechanical performance of single-crown prostheses.

Objectives: To evaluate the three-dimensional fit of abutments fabricated by the industry to those either milled or cast by a commercial laboratory and to correlate the implant-abutment connection fit with stress at fatigue failure of prostheses. Probability of survival (reliability) and fractography to characterize failure modes were also performed for cemented and screw-retained prostheses.

Methods: One-hundred and twenty-six maxillary central incisor crowns were milled to restore implants and divided in 3 cemented and 3 screwed-retained groups (n = 21/each), as follows: [Digital-Sc]: milled one-piece monolithic abutment/crown; [TiB-Sc]: milled crowns cemented onto Ti-base abutments; [UCLA]: screw-retained crown using UCLA abutments; [Digital-Ce]: milled two-piece assembly comprised by screwed monolithic abutment and a cemented crown; [TiB-Ce]: milled coping cemented onto Ti-base abutments to receive a cemented crown; [UCLA-Ce]: UCLA abutments that received an overcast coping and a cemented crown.

Influence of the composition and shades of ceramics on light transmission and degree of conversion of dual-cured resin cements.

Objective: Since the transmittance of ceramics can influence the degree of conversion (DC) of resin cements, ceramics composition and shade should be considered in the selection of resin cement. This in vitro study aimed to evaluate the effect of the transmittance of different composition, opacities and shades of ceramics on the degree of conversion of two dual-cured resin cements.

Methodology: Sixty discs were prepared from low translucency (LT) and medium opacity (MO) lithium disilicate ceramic, and zirconia ceramic (Z).

Zirconia-reinforced lithium silicate crowns: Effect of thickness on survival and failure mode.

Objective: To evaluate the reliability and failure mode of zirconia-reinforced lithium silicate (ZLS) molar crowns of different thicknesses.

Methods: Monolithic ZLS molar crowns (0.5mm, 1.

Periodontal Tissue Regeneration Using Brain-Derived Neurotrophic Factor Delivered by Collagen Sponge.

The various roles played by brain-derived neurotrophic factor (BDNF) in a multitude of tissues and at different scenarios have rendered BDNF a favorable candidate for improving tissue regeneration. Although the tested formulations of BDNF quantitatively regenerate tissue to a level similar to control groups, it resulted in significantly more instances of full regeneration.

Effect of CAD/CAM Abutment Height and Cement Type on the Retention of Zirconia Crowns.

Purpose: To evaluate Ti-Base abutment height and cement type on the retentiveness of zirconia-based restorations.

Material And Methods: Four millimeter (tall) and 2.5-mm-height (short) abutments along with temporary (provisional), glass ionomer (Meron), self-adhesive (U200), and conventional resin cement (Ultimate) were evaluated using pull-out testing (n = 10 crowns/group).

The Effect of CAD/CAM Crown Material and Cement Type on Retention to Implant Abutments.

Purpose: To evaluate the pullout resistance of CAD/CAM implant-supported crowns cemented with provisional and definitive cements on Ti-base implant abutments.

Materials And Methods: Sixty crowns were milled for use in Ti-base implant abutments and divided (n = 15/group) according to material, as follows: (a) [Pr] Temporary acrylic resin; (b) [Co-Cr] Cobalt-Chromium alloy; (c) [Zr] polycrystalline zirconia; and (d) [Ti] titanium. The cementation was performed with RelyX Temp NE (RxT) cement or RelyX U200 self-etching resin cement, under a 50 N (5 kg) load for 10 minutes.