Publications by authors named "Ilan Rozenberg"

Introduction: Individuals with chronic kidney disease (CKD) are at increased risk of thrombotic events and bleeding. Acetylsalicylic acid (ASA), an effective antiplatelet agent, is one of the most frequently used medications for both primary and secondary prevention of cardiovascular disease (CVD). However, it can also contribute to bleeding events due to its inherent antiplatelet effect.

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  • - This study examined the use of tunneled dialysis catheters (TDC) in chronic hemodialysis patients, focusing on their frequency of dysfunction and replacement over five years.
  • - Out of 625 TDC inserted, 37.4% (234) had to be replaced due to dysfunction, with diabetes identified as a significant predictor of TDC issues.
  • - The findings emphasize the growing use of TDC in dialysis, the problem of dysfunction, and the necessity for ongoing research to enhance dialysis access and catheter performance.
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Vascular access is the primary lifeline for patients with end-stage renal disease. While arteriovenous fistulas and grafts are the conventionally favored methods for dialysis therapy, certain patients may deplete these traditional vascular access options due to various reasons. In the quest for alternatives, unconventional vascular pathways could be considered, including transhepatic, trans-lumbar and trans-renal approaches.

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  • Vascular calcification, especially Intra Cranial Arterial Calcifications (ICAC), is common in maintenance hemodialysis (MHD) patients and is a key factor in the risk of cardiovascular disease.
  • A study analyzed 280 patients, finding MHD patients had higher ICAC scores (2.3) compared to a control group (1.4), with over 90% of MHD patients experiencing some level of calcification.
  • The presence of ICAC was linked to lower albumin levels and higher phosphorus and CRP levels, indicating it can predict increased mortality risk in MHD patients due to the complex interactions of inflammation and blood vessel changes.
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Introduction: The incidence of chronic kidney disease (CKD) is growing rapidly, along with the increasing geriatric population. CKD patients have higher incidence of fractures, stroke, and hospitalizations requiring rehabilitation. This is accompanied with the need for suitable rehabilitation programs to decrease disability and improve functionality to help elderly CKD patients maintain independence in activities of daily living.

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  • * This study analyzed 2,169 CKD patients, comparing aspirin users to non-users, focusing on outcomes like cardiovascular events, bleeding events, and overall mortality over an average follow-up of nearly 5 years.
  • * Results showed no significant differences in mortality or bleeding between aspirin users and non-users, and while aspirin users had higher cardiovascular event rates initially, the difference disappeared after adjusting for risk factors, suggesting aspirin may not provide the expected protective benefits in CKD patients.
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Background: Reliable vascular access is a fundamental tool for providing effective hemodialysis. Vascular access dysfunction is associated with increased morbidity and mortality among hemodialysis patients. Current vascular access guidelines strongly recommend creating an arteriovenous fistula (AVF) as the first option; however, a substantial proportion of new AVFs may not be usable.

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Introduction: The hemodialysis population is aging, worldwide. In Israel, more than half of the dialysis population is older than 68 years. The policy for vascular access among this population is still a matter of debate, with several studies demonstrating conflicting results.

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Background: As the geriatric population is growing rapidly, so is the prevalence of chronic kidney disease (CKD). Suitable rehabilitation programs are needed to decrease disability and improve functionality to maintain independence in activities of daily life.

Aims: To assess the impact of CKD on the efficacy of rehabilitation in the geriatric population.

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Introduction: Coronavirus disease is associated with increased morbidity and mortality in maintenance hemodialysis (MHD) patients. Recent breakthrough infection in vaccinated people has led some authorities to recommend a booster dose for patients fully vaccinated 5-8 months ago. We aimed to assess the humoral response of MHD patients following a booster dose with the BNT162b2 vaccine.

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Introduction: Chronic kidney disease is associated with an increased risk of vascular events and bone fractures, and its prevalence is increasing. Despite the high frequency of strokes and bone fractures in the hemodialysis (HD) population, the few studies on rehabilitation outcomes in this population are controversial. The current study assessed the efficacy of inpatient rehabilitation for hemodialysis patients.

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Background: Predicting the mortality risk of patients un-dergoing hemodialysis (HD) is challenging. Cell-free DNA (cfDNA) is released into circulation from dying cells, and its elevation is predictive of unfavorable outcome. In a pilot study, we found post-HD cfDNA level to be a predictor of all-cause mortality.

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Purpose: The incidence of stroke in patients undergoing hemodialysis (HD) is eight-to-ten times greater than that of the general population. However, data on the outcome of stroke in these patients are limited.

Methods: In this retrospective observational cohort study, electronic medical records of all patients undergoing HD from 1.

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Infection is one of the leading causes of mortality in dialysis patients, second only to cardiovascular disease. This retrospective study assessed the efficacy and clinical outcomes of influenza vaccination among hemodialysis (HD) patients. In the 2014-2015 season, 104 of 164 (63.

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Background: Idiopathic membranous nephropathy (IMN) is one of the most common causes of nephrotic syndrome (NS) in Caucasian adults. Most patients have good renal prognosis, but 30-40% may progress to end stage renal disease (ESRD).

Objectives: To evaluate the efficacy and safety of immunosuppressive treatment (IST) in high-risk patients.

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Background: Upper respiratory tract infection (URTI) occurs frequently in the general population and is considered a benign self-limited disease. Dialysis patients constitute a high risk population whose morbidity and mortality rate as a result of URTI is unknown.

Objectives: To assess the local incidence, morbidity and mortality of URTI in dialysis patients compared to the general population.

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