The Prevalence and Factors Associated with Coronary Heart Disease in Patients with Gout.

Unlabelled: Gout is associated with increased risk of cardiovascular disease (CVD) morbidity and mortality. Therefore, an association between coronary heart disease (CHD) and gout deserves careful examination.

Aim: .

[Relationship between the intima-media complex thickness, the risk factors of cardiovascular diseases, and the level of C-reactive protein in gouty patients].

Aim: To estimate a relationship between the intima-media thickness (TIM), cardiovascular risk (CVR) factors, and the level of C-reactive protein (CRP) in gouty patients.

Subjects And Methods: Eighty-nine patients at an interattack interval were examined. The patients' mean age was 46.

[Use of metformin (siofor) in patients with gout and insulin resistance (pilot 6-month results)].

Aim: To evaluate metformin efficacy and safety in patients with gout and insulin resistance (IR).

Material And Methods: The trial included 26 patients with gout (criteria of the American collage of rheumatologists) and IR (index HOMA). The inclusion criteria were the following: absence of antigout therapy, normal hepatic and renal function, rejection of alcohol.

[Severity of a female gout course].

Aim: Comparison of a gout course in males and females.

Material And Methods: The trial enrolled 34 patients (17 females and 17 males). The patients were matched by age and the disease duration.

[The effectiveness and safety of nimesulide (nimesile) in patients with gouty arthritis].

Patients with gout are at a high risk for drug-induced complications associated with the use of nonsteroidal anti-inflammatory drugs due to the baseline renal and hepatic abnormalities, metabolic disturbances, and concomitant diseases, such as arterial hypertension or type 2 diabetes mellitus. In this connection, it is expedient to use safer selective cycloxygenase-2 (COG-2) inhibitors. However, there are only single reports dealing with studies of the effectiveness and safety of selective COG-2 inhibitors in gout.

[Insulin resistance syndrome in patients with gout and its influence on formation of clinical characteristics of the disease].

Aim: To evaluate the occurrence of immunoresistance (IR) syndrome in gout and its correlation with a gout course.

Material And Methods: Anthropometric parameters, blood lipid spectrum, levels of glucose, uric acid (UA), immunoreactive insulin, HOMA index were studied in 55 male patients with gout (mean age 50.1 +/- 7.

[The role of gastroduodenal diseases in the development of cardiac arrhythmia of the sick sinus syndrome type].

A total of 105 patients with suspected sick sinus syndrome were examined. All of them underwent transesophageal pacing and endoscopical investigation. A relationship is shown between lesions of the gastrointestinal tract and emergence of the sinus vagal depression leading to various disturbances of cardiac rhythm.