Publications by authors named "Ikuta Y"

Background: Postoperative osteolysis may be observed around poly-l-lactic acid (PLLA) pins in osteochondral fragments fixation for an osteochondral lesion of the talus (OLT). Hydroxyapatite (HA) improves biocompatibility, osteoconductivity, and mechanical strength when added to PLLA. This study aimed to compare the characteristics of osteolysis and clinical outcomes of fixation for OLT with PLLA pins vs PLLA/HA pins.

View Article and Find Full Text PDF

We synthesized lecithin-modified zirconia (LMZ) as an adsorbent, solid-phase extractant, and stationary phase for organic compounds such as organic acids or amino acids. The molecular selectivity of LMZ was evaluated through high-performance liquid chromatography (HPLC). LMZ exhibits electrostatic and hydrophobic interactions with organic compounds that depend on the pH of the mobile phase.

View Article and Find Full Text PDF

Objectives: To investigate the effectiveness of placing an indicator light indicating inadequate ventilation near the face mask during positive-pressure ventilation with respiratory function monitors (RFMs) in neonatal resuscitation. The study is a three-group, randomised, controlled, crossover simulation trial.

Methods: Paediatrics residents, neonatology fellows, and attending neonatologists at a single neonatal intensive care unit.

View Article and Find Full Text PDF
Article Synopsis
  • Chronic stress on the second metatarsal head in patients with hallux valgus can lead to osteoarthritis and dislocation of the second metatarsophalangeal joint.
  • A study analyzed 115 HV feet, separating them into two groups based on dislocation presence and further categorizing those without dislocation by osteoarthritis status.
  • Results indicated that greater protrusion of the second metatarsal and specific angles were linked to higher risks of dislocation and osteoarthritis in the joint.
View Article and Find Full Text PDF

Heterotopic ossification (HO) in Achilles tendon often arises due to endochondral ossification during the healing process following trauma. Retinoic acid receptor γ (RARγ) plays a critical role in this phenomenon. This study aims to elucidate the therapeutic effects of CD1530, an RARγ selective agonist, along with the contributing cells, in Achilles tendon healing, utilizing a cell lineage tracing system.

View Article and Find Full Text PDF

The level of dynamic mechanical instability between the bony parts of the ankle joint provides important information on biomechanical function. However, the dynamics of the distance between the talus and lateral malleolus during gait remain unclear. This study aimed to compare the distance between the talus and lateral malleolus and the ankle joint angles during the stance phase of gait between individuals with chronic ankle instability (CAI) and healthy adults.

View Article and Find Full Text PDF
Article Synopsis
  • - The study investigates the effects of posterior talofibular ligament (PTFL) injury on outcomes after arthroscopic repair of the anterior talofibular ligament (ATFL) in patients with chronic lateral ankle instability (CLAI).
  • - MRI findings showed that PTFL thickness and cross-sectional area were larger in people with CLAI, and PTFL injuries were associated with higher recurrence rates of ankle instability post-surgery.
  • - While PTFL injuries didn’t significantly affect clinical scores after surgery, the presence of these injuries correlated with a greater likelihood of instability recurrence and associated injuries to other ligaments.
View Article and Find Full Text PDF
Article Synopsis
  • * The choice of treatment depends on factors such as lesion size, shape, location, and presence of cysts, with osteochondral fragment fixation being particularly beneficial as it maintains the original cartilage and bone structure.
  • * Recent studies indicate that fixation for OLT is effective for both acute and chronic lesions, even expanding to include smaller-sized lesions with positive clinical results.
View Article and Find Full Text PDF
Article Synopsis
  • This study investigates the relationship between Hounsfield unit (HU) measurements in subchondral bone and the condition of articular cartilage in ankle osteoarthritis (OA).
  • Researchers gathered talar articular surfaces from 14 ankles and assessed them histologically and via CT imaging, correlating HU values with cartilage degeneration.
  • The findings reveal that as OA worsens, both cartilage defects and subchondral bone thickness increase, with significant correlations between HU values and cartilage health observed, suggesting that HU measurement can help evaluate joint surface conditions.
View Article and Find Full Text PDF
Article Synopsis
  • Surgical treatment of osteochondral lesions of the talus (OLT) often has variable outcomes for athletes, particularly related to medial OLT with underlying structural issues.
  • The study examined 81 ankles in 74 patients, focusing on the impact of preoperative abnormalities in the posterior tibial tendon (PTT) as seen in MRI scans.
  • Results indicated that patients with PTT abnormalities showed worse postoperative clinical outcomes, including lower JSSF scores and decreased arch height compared to those without such abnormalities.
View Article and Find Full Text PDF

The forced turnout has a perceived risk of development of hallux valgus (HV) in ballet dancers. We determined how the forced turnout affects the sagittal mobility of the first tarsometatarsal (TMT) joint, which is one of the pathogenic factors of HV development. Seventeen female ballet dancers (body mass index: 18.

View Article and Find Full Text PDF
Article Synopsis
  • A 15-year-old boy suffered a medial cuneiform nonunion after using conservative treatment for several months, leading to surgical intervention involving open reduction, internal fixation, and bone grafting.
  • Post-surgery, the patient achieved full recovery and returned to competitive sports, evidenced by a perfect SAFE-Q score reflecting improvements in pain, physical functioning, and overall well-being 21 months later.
View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to validate clinical prediction rules for identifying locomotive syndrome in older adults living in the community, which can help in early detection.
  • Researchers evaluated physical function tests and demographic factors from 280 participants, mainly women with an average age of 74.8 years, to assess the severity of locomotive syndrome.
  • The results showed that the first two predictive models had moderate accuracy in discriminating the stages of locomotive syndrome, indicating their reliability for use in this population.
View Article and Find Full Text PDF

Background: Ankle osteoarthritis (OA) mainly arises from trauma, particularly lateral ligament injuries. Among lateral ligament injuries, ankles with calcaneofibular ligament (CFL) injuries exhibit increased instability and can be a risk factor ankle OA progression. However, the relationship between CFL injury and OA progression remains unclear.

View Article and Find Full Text PDF
Article Synopsis
  • This study aimed to measure the vertical movement between the first metatarsal and medial cuneiform bones during walking in young adults with different levels of hallux valgus.
  • It included 34 participants divided into three groups based on the severity of hallux valgus and used ultrasound alongside motion analysis for assessment.
  • The results showed that as the severity of hallux valgus increased, the medial cuneiform shifted more downward during specific phases of walking, indicating greater joint mobility and highlighting the importance of early prevention for this condition.
View Article and Find Full Text PDF

Background: Arthroscopic ankle arthrodesis (AAA) has become popular because of its higher rate of bone union, lower invasiveness, and shorter hospital stays compared to those of open arthrodesis. However, postoperative malalignment is often observed for severe varus deformity, which can cause nonunion, pain, and adjacent joint arthrosis. A compression staple can provide a persistent, strong compressive force on the bone surface.

View Article and Find Full Text PDF

Background: Difficulties in the accurate evaluation of tibiofibular clear space in plain radiographs are diagnostic problems in the clinical setting of syndesmosis injury. This study aimed to quantify the anterior tibiofibular gap (ATFG) with weight-bearing using ultrasonography.

Methods: In total, 32 healthy adults (16 men and 16 women) with 64 feet participated in this cross-sectional study.

View Article and Find Full Text PDF
Article Synopsis
  • Falls among the elderly lead to serious health issues and a decline in quality of life, prompting the study of ankle position sense as a potential risk factor for falls.
  • The study involved 54 feet from 28 elderly patients and compared their ankle position sense and fall history to those of 5 healthy volunteers.
  • Results indicated that elderly individuals had higher errors in ankle position sense, especially those with a history of falling, suggesting that impaired internal rotation awareness is a significant risk factor for falls in older adults.
View Article and Find Full Text PDF

This study aimed to estimate the factors that cause differences in competition level based on the competition performance structure among university student decathletes in Japan. The results of factor analysis using the maximum likelihood method (Oblimin rotation), assuming a five-factor structure estimated from parallel analysis and the information criterion, revealed the following competitive performance structures: "running speed and body projection," "running endurance," "rotational throwing power," "translational throwing power," and "vertical leaping power." Some of these were similar to the competitive performance structures of the world's top athletes, but they were found to have a unique structure: two throwing powers.

View Article and Find Full Text PDF
Article Synopsis
  • Foot arch dynamics play a crucial role in dynamic postural control, especially in adolescent athletes, but their effects are not well understood.
  • This study aimed to investigate how foot arch stiffness, intrinsic foot muscle structure, and toe strength relate to postural stability during jump landings and rebounds.
  • Results indicated that athletes with stiffer arches showed poorer stability and performance in dynamic balance tasks compared to those with normal or flexible arches, suggesting that arch stiffness can negatively impact athletic performance.
View Article and Find Full Text PDF

In placing the medial suture button for syndesmosis injury, the risk of great saphenous vein and saphenous nerve injury has been reported. This study aimed to determine the safe insertion angle of the guide pin to avoid saphenous structure injury during suture button fixation. The incidence of saphenous structure injury was investigated using 8 legs of cadavers.

View Article and Find Full Text PDF

Purpose: Repeated ankle sprains can lead to chronic lateral ankle instability (CLAI). It is unclear whether CLAI causes pain unless complicated by intra-articular lesions. This study aimed to analyze the characteristics of pain and the relationship between pain and intra-articular pathology in patients with CLAI.

View Article and Find Full Text PDF

Background: Emicizumab, a factor (F) VIIIa-function mimetic bispecific antibody (BsAb) to FIXa and FX, has become an indispensable treatment option for people with hemophilia A (PwHA). However, a small proportion of PwHA still experience bleeds even under emicizumab prophylaxis, as observed in the long-term outcomes of clinical studies. A more potent BsAb may be desirable for such patients.

View Article and Find Full Text PDF
Article Synopsis
  • - The study investigates whether measuring changes in the morphology of the calcaneofibular ligament (CFL) using MRI can quantitatively assess CFL injuries, especially in the context of chronic lateral ankle instability (CLAI).
  • - It involved 64 ankles categorized into two groups: those that had CFL repair along with anterior talofibular ligament (ATFL) repair and those that only had ATFL repair, analyzing specific angles on preoperative MRI to determine the effectiveness of these measurements.
  • - Results showed that the angles measured (CFLCA and FCA) had high sensitivity and specificity for identifying CFL injuries, with the combination of both angles enhancing diagnostic accuracy, indicating their potential utility in clinical evaluations of ACL injuries.
View Article and Find Full Text PDF