Nascent deep microbleeds and stroke recurrences.

Background: Cerebral microbleeds (MBs) on gradient echo T2*-weighted magnetic resonance imaging (MRI) scans are associated with the severity of cerebral microangiopathies. This study investigated the contributions of nascent deep MBs to stroke recurrence.

Methods: We prospectively analyzed nascent deep MBs in patients admitted to our hospital who were treated for index strokes between April 2004 and November 2009.

Nascent lobar microbleeds and stroke recurrences.

Background: Lobar microbleeds (MBs) are occasionally visible on gradient-echo T2*-weighted (T2*-w) magnetic resonance imagings (MRIs) in patients with deep intracerebral hemorrhages (ICHs). This study investigated the contribution of nascent lobar MBs to occurrences of deep ICHs.

Methods: We prospectively analyzed nascent lobar MBs in patients admitted to our hospital who were treated with index strokes between April 2004 and November 2009.

Antithrombotic drug uses and deep intracerebral hemorrhages in stroke patients with deep cerebral microbleeds.

Background: It has been suggested that antiplatelet or anticoagulant drugs elevate the rate of intracerebral hemorrhage (ICH) in patients with cerebral microbleeds (MBs). To investigate the mechanism by which antiplatelet drugs or warfarin may contribute to deep ICH occurrences in patients with deep MBs, we prospectively analyzed deep ICH occurrences in 807 consecutive patients (351 females and 456 males; mean age ± standard deviation 69.8 ± 12.

The difference in location between traumatic cerebral microbleeds and microangiopathic microbleeds associated with stroke.

Background And Purpose: Microbleeds (MBs) are low-intensity spots on gradient echo T2*-weighted MRI frequently associated with cerebral microangiopathies resulting in stroke. MBs can also be caused by cerebral axonal injuries. We compared the location of MBs associated with cerebral microangiopathies with those associated with trauma.

The number of microbleeds on gradient T2*-weighted magnetic resonance image at the onset of intracerebral hemorrhage.

Objective: Deep intracerebral hematoma (ICH) is frequently associated with microbleed (MB) arising from degenerated MB. Increased numbers of MB are correlated with increased age, and we examined a possible relationship between MB number and ICH onset in younger patients.

Methods: Excluding patients with ICH and a history of ICH, we examined the number of MB and other risk factors in 195 patients with deep ICH (97 male, 98 female) consecutively admitted to our hospital.

Dynamics of dot-like hemosiderin spots on T2*-weighted MRIs associated with stroke recurrence.

Background And Purpose: Dot-like low-intensity spots (dot-like hemosiderin spots: dotHSs) on gradient echo T2*-weighted (-w) brain magnetic resonance imaging (MRIs) are frequently associated with cerebral small vessel disease (SVD), including deep intracerebral hemorrhages and lacunar infarctions. This study investigated how numbers of newly appeared dotHSs contribute to recurrent SVD.

Methods: We prospectively analyzed numbers of newly appeared dotHSs in 12 patients with prior SVD (8 males, 4 females; mean 67.

Hematoma size in deep intracerebral hemorrhage and its correlation with dot-like hemosiderin spots on gradient echo T2*-weighted MRI.

Background And Purpose: Dot-like low intensity spots (dot-like hemosiderin spots: dotHSs) on gradient echo T2*-weighted MRI have been histologically diagnosed to represent old cerebral microbleeds associated with microangiopathies. They have also been correlated to the fragility of small vessels and the tendency to bleed. Therefore, a substantial number of dotHSs might be associated with a large-sized, deep intracerebral hematoma (ICH).

[Study on hemosiderin deposition after intracerebral hemorrhage].

Background And Purpose: Hemosiderin degenerated from intracerebral hematoma (ICH) can be visualized as low intensity on gradient-echo T2*-weighted (T2*-w) MRI, which is sensitive for hemosiderin. We studied the factors associated with the hemosiderin deposition on T2*-w MRI after ICH.

Methods: We analyzed T2*-w MRIs in 72 outpatients with past ICH (46 males, 26 females, 28-89 (60.

Identification of Respiratory Neurons Regenerating Axons into Peripheral Nerve Grafts in Adult Rats.

The present aimed to identify the origin of medullary and upper cervical respiratory neurons regenerating their axons into the peripheral nerve grafts in adult rats. We employed an antidromic activation technique and a retrograde horseradish peroxidase (HRP) tracing method for determining the origins of the regenerating axons. Autologous segments of the common peroneal nerve were successfully implanted ventrolaterally into the proximal cut end of the C2 spinal cord hemisection (n = 24).