Publications by authors named "Ikue Chijimatsu"

Article Synopsis
  • Infants with KMT2A (MLL)-rearranged acute lymphoblastic leukemia (MLL-r ALL) have poor outcomes even with aggressive treatments, like stem cell transplants.
  • Epigenetic changes are believed to play a major role in the development of this type of leukemia, leading researchers to explore epigenetic drugs as potential therapies.
  • A specific case showed that after a relapse post-transplant, the infant achieved and maintained remission for 10 months with azacitidine, before successfully undergoing a second stem cell transplant.
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The production of factor VIII (FVIII) inhibitory antibodies is a serious problem in patients with hemophilia A. Immune tolerance induction (ITI) is the only strategy proven to eradicate persistent inhibitors and has been shown to be successful in 70 % of patients with hemophilia A. However, a minority of hemophilia patients present life-long inhibitors.

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Filamentous fungi were detected in the blood culture of a one-year-old boy after autologous peripheral blood stem cell transplantation. The patient was suspected to have aspergillosis and received micafungin. Fungi were isolated on potato dextrose agar medium and incubated at 37℃ for 2-5 days.

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