Publications by authors named "Ikram U Haq"
The aim of the present research was the efficient degradation of industrial textile wastewater dyes using a very active cloned laccase enzyme. For this purpose, potent laccase-producing bacteria were isolated from soil samples collected from wastewater-replenished textile sites in Punjab, Pakistan. The laccase gene from locally isolated strain LI-81, identified as , was cloned into vector pET21a, which was further transformed into BL21 codon plus.
View Article and Find Full Text PDFAim: This study aims to conduct a comprehensive analysis and scientometric evaluation of the top 100 most cited publications in the field of implant prosthodontics, authored by individuals affiliated with nations of the Middle East and North Africa (MENA) region.
Materials And Methods: In October 2023, the 100 most cited articles were gathered from the Web of Science database using the bibliometric research technique. The analysis was conducted on bibliometric indicators, including the distribution of articles over time, authorship, design of study, field of study, nature of research, contribution from various countries in MENA, international research collaboration, and most frequently used keywords by authors.
Glucose-derived acids for the further production of value-added medicine, food additives, and polymers, will promote lignocellulosic biomass biorefinery industry. In response to the diversity and complexity, a new method was established by employing high performance anion exchange chromatography (HPAEC) coupled with a CarboPac™ PA200 column, for the precise and fast determination of glucose, gluconic acid, glucuronic acid, 2-ketogluconic acid, 5-ketogluconic acid and glucaric acid. Based on the analysis of tiny varieties in retention behavior, a gradient elution mode was designed and optimized for the quantitative and qualitative analysis.
View Article and Find Full Text PDFRole of microbial laccases in valorization of lignocellulosic biomass to bioethanol.
Front Bioeng Biotechnol
July 2024
The persistent expansion in world energy and synthetic compounds requires the improvement of renewable alternatives in contrast to non-sustainable energy wellsprings. Lignocellulose is an encouraging feedstock to be utilized in biorefineries for its conversion into value-added products, including biomaterials, biofuels and several bio-based synthetic compounds. Aside from all categories, biofuel, particularly bioethanol is the most substantial fuel derived from lignocellulosic biomass and can be obtained through microbial fermentation.
View Article and Find Full Text PDFAim: The aim of this study was to identify and appraise the bibliometric properties of top 100 most-cited articles on regenerative periodontics surgery (RPS).
Materials And Methods: The bibliometric research technique was conducted using a dataset comprising the 100 highly cited articles obtained from Elsevier's Scopus database on RPS. Information regarding the growth of articles by year, number of citations, citations per year, study design, study field, modalities, journals, authors, and countries were extracted for each article.
Article Synopsis
- * A significant increase in orthodontics research output was observed, with Arab nations contributing 5.02% to global research and experiencing a rise from 1.24% to 10.94% of publications.
- * Saudi Arabia was the most productive country, while collaboration with the U.S. was common; however, documents co-authored with Turkey had the highest citation impact, indicating an upward trend in research quality and collaboration.
Background: The effects of disease-causing MYBPC3 or MYH7 genetic variants on atrial myopathy, atrial fibrillation (AF) clinical course, and catheter ablation efficacy remain unclear.
Objectives: The aim of this study was to characterize the atrial substrate of patients with MYBPC3- or MYH7-mediated hypertrophic cardiomyopathy (HCM) and its impact on catheter ablation outcomes.
Methods: A retrospective single-center study of patients with HCM who underwent genetic testing and catheter ablation for AF was performed.
A Bibliometric Analysis of Most Cited Papers on Vesiculobullous Oral Lesions.
J Int Soc Prev Community Dent
January 2024
Aim: A well-known method for quantitatively evaluating scholarly work is bibliometric analysis. Best-cited papers raise awareness of the influential publications and patterns in the literature on a specific subject. The aim was to conduct bibliometric analysis to determine most cited articles on vesiculobullous oral lesions.
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- Hemicellulases are enzymes that break down hemicelluloses, which are common polysaccharides, and thermophilic hemicellulases from microbes are being researched for their potential in biofuel production due to their heat resistance and structural complexity.
- Recent studies are focused on understanding how these enzymes work, their stability at high temperatures, and their specific functions, which could lead to advancements in biotechnology and industrial applications.
- The article emphasizes the importance of improving thermophilic hemicellulases for eco-friendly catalysis and highlights challenges like high costs and the need for efficient bioprocesses using microbial consortia to make biofuel production more commercially viable.
Aims: ECG abnormalities are often the first signs of arrhythmogenic right ventricular cardiomyopathy (ARVC) and we hypothesized that an artificial intelligence (AI)-enhanced ECG could help identify patients with ARVC and serve as a valuable disease-detection tool.
Methods And Results: We created a convolutional neural network to detect ARVC using a 12-lead ECG. All patients with ARVC who met the 2010 task force criteria and had disease-causative genetic variants were included.
Article Synopsis
- - Esterases are enzymes that break down ester bonds into water-soluble compounds and are widely used in various industries due to their commercial value and versatility.
- - Microbial esterases are preferred in industrial applications because they are cost-effective, provide high yields, and are not affected by seasonal changes.
- - As industries increasingly focus on eco-friendly practices, the review highlights the importance of bacterial esterases in various sectors, explores their structural properties and recent research advancements for optimizing their use.
Publication Trends and Collaborative Patterns in Periodontics Research from Saudi Arabia: A Bibliometric Analysis.
J Int Soc Prev Community Dent
December 2023
Aim: To perform a comprehensive bibliometric analysis encompassing all articles published on periodontics from Saudi Arabia.
Materials And Methods: Using the Scopus database on June 8, 2023, the search term "Periodontic*" was entered in the primary search bar to extract all documents published on periodontics. Following, the year filter was applied to include articles published from the earliest available date until the date of data collection, excluding 2023.
Article Synopsis
- Okra is a widely consumed vegetable facing challenges from salinization and climate change, necessitating the development of salt-tolerant cultivars for sustainable production.
- A study evaluated 100 okra genotypes for salt tolerance by assessing their morphological and physio-biochemical responses under controlled and saline conditions.
- Results revealed significant genetic variability among genotypes, with five genotypes (95, 111, 133, 99, and 128) demonstrating both high yield and salt tolerance, essential for breeding efforts.
Article Synopsis
- Excessive fossil fuel use is leading to environmental issues and a pressing need to transition to renewable energy sources, particularly from lignocellulosic biomass.
- The study investigates the joint production of biohydrogen and biomethane using a lesser-studied halophyte, optimizing various reaction parameters like temperature, pH, and substrate concentration.
- Optimal conditions resulted in a significant increase in both biohydrogen (66 mL) and biomethane (343 mL) yields, showcasing the halophyte's potential as a valuable renewable energy source.
Outflow tract ventricular arrhythmias are the most common type of idiopathic ventricular arrhythmia. A systematic understanding of the outflow tract anatomy improves procedural efficacy and enables electrophysiologists to anticipate and prevent complications. This review emphasizes the three-dimensional spatial relationships between the ventricular outflow tracts using seven anatomical principles.
View Article and Find Full Text PDFResearch Performance of Saudi Arabia in Endodontics: A Bibliometric Analysis.
J Int Soc Prev Community Dent
April 2023
Endodontics is a subdivision of dentistry that deals with diseases and injury of the soft tissues inside the teeth. The current study aimed to investigate the bibliometric properties of endodontics publications contributed by Saudi Arabia from 2010 to 2022. The quantitative bibliometric research method was applied to the meta-data retrieved from the Web of Science on December 7, 2022.
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- DNA polymerases are essential enzymes that replicate genetic information in nucleic acids, ensuring that every living cell can accurately copy its genomic DNA during cell division.
- Thermostable DNA polymerases are particularly valuable in biotechnology and molecular biology, facilitating techniques like DNA cloning, sequencing, and PCR.
- Research continues into the discovery and engineering of various DNA polymerases, with ongoing studies aimed at understanding their specialized functions and developing new applications for them.
Article Synopsis
- Despite advancements in health care, the rise of viral infections poses significant challenges in terms of health and financial burdens globally, particularly highlighted by over ten major epidemics in the 21st century, including COVID-19.
- The emergence of new viral strains and drug-resistant paths necessitates innovative therapeutic strategies, including the development of multi-target antiviral drugs inspired by natural resources and modern gene therapy techniques.
- The review covers the mechanisms of viral infections, advances in detection strategies, current approaches to combat these pathogens, their limitations, and novel potential treatment targets.
Effect of pretreatment strategies on halophyte to improve saccharification using thermostable cellulases.
Front Bioeng Biotechnol
February 2023
Bioethanol is believed to be an influential revolutionary gift of biotechnology, owing to its elevating global demand and massive production. Pakistan is home to a rich diversity of halophytic flora, convertible into bounteous volumes of bioethanol. On the other hand, the accessibility to the cellulosic part of biomass is a major bottleneck in the successful application of biorefinery processes.
View Article and Find Full Text PDFCircular RNAs: Insights into Clinical and Therapeutic Approaches for Various Cancers.
Curr Protein Pept Sci
March 2023
Article Synopsis
- Circular RNAs (circRNAs) are unique noncoding RNAs formed through a process called exon back splicing, and they play crucial roles in regulating gene expression and cellular functions.
- Abnormal levels of circRNAs are commonly found in cancer, contributing to tumor growth, invasiveness, and evasion of cell death, which suggests their potential as clinical biomarkers and therapeutic targets.
- This review highlights the current understanding of circRNA functions, their promise in disease diagnosis and treatment, and the challenges that come with utilizing them in clinical settings.