Fabrication and characterization of gold nanoflowers formed via chitosan-tripolyphosphate template films for biomedical applications.

Flowerlike gold nanostructure was facilely prepared by the seed-mediated growth of gold nanoparticles in chitosan-TPP template films. Firstly, chitosan nanoparticles, spontaneously formed by inter and/or intra cross-linking with TPP, were transformed into gel-type of chitosan-TPP films under strong sonication process. After then, gold seeds (1-3 nm) were entrapped in chitosan-TPP films via electrostatic interactions, and the resulting films were subsequently used as a template for growing gold nanoparticles and subsequent formation of anisotropic gold nanoflowers.

Effects of dopamine concentration on energy transfer between dendrimer-QD and dye-labeled antibody.

The Unified Parkinson's Disease Rating Scale (UPDRS) is currently used to assess Parkinson's disease, and is a key method for determining the progression of disease based on the gross findings of patients. However, this method cannot quantify the extent of disease of patients, which means the administration of drugs cannot be determined on a real-time basis. Thalamotomy also causes discomfort and pain to the patients, and adversely affects treatment as it is performed following the onset of symptoms.

Evaluation of the effects of biodegradable nanoparticles on a vaccine delivery system using AFM, SEM, and TEM.

Hepatitis B is a deadly disease, and is carried by 30% of the world's population. Antibodies are produced through a series of three manual vaccinations during infancy and childhood. However, the current needle vaccination not only induces pain in patients, but also can be inconvenient to administer.