Endocrine disruptors in Adansonia digitata (Linn) extract induce alteration of female Wistar rats' oestrous cycle, hormone and lipid profiles.

Objective: Hexane-acetyl acetate (HAAF) and acetyl acetate-methanol fractions (AAMF) but not aqueous methanol (AQMF) and aqueous fractions (AQF) of Adansonia digitata Linn root bark induce reproductive effects in female Wistar rats. The current study investigated the exclusive components of HAAF, AAMF, AQMF, and AQF of Adansonia digitata Linn root bark and the effect of AAMF on the female Wistar rat's oestrous cycle progression, and hormone and lipid profiles.

Methodology: Gas chromatography and mass spectrometry explored the components of HAAF, AAMF, AQMF, and AQF.