Publications by authors named "Ihtisham Habib"

Colchicine, a long-established anti-inflammatory medication, has emerged as a potential therapeutic agent for secondary prevention of stroke. This systematic review and meta-analysis aimed to evaluate the efficacy and safety of colchicine in preventing secondary stroke by comprehensively synthesizing available evidence. A systematic literature search was conducted across multiple electronic databases from inception to November 15, 2024, using comprehensive search strategies.

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Lipoprotein(a) (Lp(a)) has emerged as a significant cardiovascular risk factor, particularly in patients with ischemic heart disease (IHD). This systematic review and meta-analysis aimed to synthesize evidence on the impact of Lp(a) levels on cardiovascular outcomes in IHD patients. A comprehensive literature search was conducted across multiple databases, covering publications from January 2016 to October 2024.

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Article Synopsis
  • Atrial fibrillation (AF) patients with liver disease face challenges in anticoagulation management due to their higher risks for both blood clots and bleeding.
  • This study compared the effectiveness and safety of direct oral anticoagulants (DOACs)—apixaban, rivaroxaban, and dabigatran—against vitamin K antagonists (VKAs), finding that all DOACs were superior, particularly apixaban, in preventing strokes and bleeding events.
  • While promising, the research is limited by the mostly observational studies included, indicating the need for more large-scale trials to determine the best dosing and management strategies for these patients.
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Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder with diverse clinical manifestations. Among these, ocular complications are notably prevalent, affecting up to one-third of patients. One rare but serious ocular complication of SLE is central retinal artery occlusion (CRAO), which can result in significant vision loss.

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