Early, Forme Fruste keratoconus and normal thin cornea, evaluation of sensitive parameters by combined Placido Scheimpflug topography.

Purpose: To determine the sensitive indices distinguishing forme-fruste keratoconus (FFKC) and early keratoconus (early KC) from thin normal corneas, and their cutoff values using Sirius topography.

Methods: 156 eyes with normal thin corneas < 500 um (group 1), 99 eyes with early KC (group 2) and 41 eyes with FFKC (group 3), were assessed retrospectively for: corneal keratometric indices, pachymetry indices, corneal aberrations, elevation indices; thinnest corneal point elevation, Q value, root mean square (RMS) withRMS/ area (RMS/A); and KC summary indices of front and back surfaces; surface asymmetry index (SIf, SIb), elevation at KC vertex (KVf, KVb), Baiocchi-Calossi-Versaci index (BCVf, BCVb) and summation of its vector (BCV). Cutoff values were calculated.

Eight-years Egyptian experience of Boston type I keratoprosthesis following failed penetrating keratoplasty or ocular surface disease.

Purpose: To evaluate the outcome and complications after implantation of the Boston type I keratoprosthesis (Kpro) in two groups of eyes.

Methods: We retrospectively reviewed records of 28 eyes with failed Penetrating keratoplasty (PKP) (Group A) and 31 eyes with severe ocular surface diseases who implanted Kpro. Follow-up was performed for a mean 37 months.

Angle Kappa agreement between Scheimpflug tomography, combined placido Scheimpflug and combined slit scanning placido systems.

Purpose: To compare the measured or calculated angle Kappa using Oculus pentacam HR, Sirius and Orbscan III devices.

Patients And Methods: A prospective randomized cohort study, conducted on 47 eyes of 47 healthy orthotropic individuals, with an age range of 18-50 years and a corrected Snellen's distance visual acuity (CDVA) of 0.8 decimal or better.

Distribution of angle lambda and pupil offset as measured by combined Placido Scheimpflug Topography.

Background: Angle lambda is the angle between the pupillary axis and the line of sight. It is important for accurate centration during anterior segment surgery. The purpose of this study is to identify the distribution of angle lambda and pupil center offset as measured by a combined placido disc Scheimpflug topography system.

Angle κ Measurement and Its Correlation with Other Ocular Parameters in Normal Population by a New Imaging Modality.

Significance: This study obtained normative database for angle κ using Orbscan 3. The average angle κ values were 2.3 ± 1.

Transepithelial Laser versus Alcohol Assisted Photorefractive Keratectomy Safety and Efficacy: 1-Year Follow-up of a Contralateral Eye Study.

Purpose: To compare single-step transepithelial photorefractive keratectomy (TPRK) to conventional alcohol assisted epithelial removal then photorefractive keratectomy (AAPRK) regarding pain, epithelial healing, visual acuity, corneal haze measured subjectively and objectively, higher order aberrations changes, contrast sensitivity and vector analysis of astigmatic correction with one year follow-up.

Methods: A prospective double-blind randomized study of 29 subjects (58 eyes) who underwent myopic aberration-free laser correction by smart pulse technology using Schwind Amaris 1050 Hz with 1-year follow-up. Right eye was randomly treated by AAPRK or TPRK.

Topographic, elevation, and keratoconus indices for diagnosis of keratoconus by a combined Placido and Scheimpflug topography system.

Purpose: To determine the accuracy of various corneal parameters in keratoconus diagnosis using Scheimpflug camera combined with Placido disk corneal topography (Sirius, CSO).

Methods: One hundred and fifteen keratoconic eyes (group1) and a 111 normal eyes (group2) were assessed prospectively between March 2018 and July 2019 for: corneal keratometric indices (K1, K2, sim K, apex curvature) at different corneal rings of both corneal surfaces, central corneal thickness (CCT), thinnest corneal thickness (TL), corneal asphericity (Q), elevation at thinnest point, root mean square (RMS), and root mean square per area (RMS/A) in spherical, aspheric and aspherotoric reference for both corneal surfaces and keratoconus summary parameters; surface asymmetry index of front and back (SIf, SIb respectively), elevation at keratoconus vertex front and back (KVf, KVb respectively), Baiocchi Calossi Versaci front and back index (BCVf, BCVb) and its vector summation (BCV) and convergence radius and cutoff value for each was calculated.

Results: All studied indices were significantly different between the two groups.

Repeatability and Interchangeability of Topometric, Anterior Chamber and Corneal Wavefront Data Between Two Scheimpflug Camera Devices.

Purpose: This study aims to assess the intra-operator repeatability and correlation of the Pentacam HR (device 1) and Sirius (device 2) in measuring anterior segment parameters and to evaluate the agreement of their readings and therefore their interchangeability in a clinical setting.

Methods: This is a prospective non-randomized study was conducted on the right eyes of 102 subjects coming to Eye World Hospital, Giza, Egypt. With each machine, four scans were taken by a single examiner.

Expanded use of transconjunctival orbitotomy in management of different orbital tumors at different locations.

Purpose: To assess the surgical outcomes of transconjunctival approach in management of different orbital tumors at different locations.

Methods: This prospective, non-comparative, clinical interventional study was conducted in the period between March 2017 and January 2020 and included 61 patients with histologically proved orbital tumors. In all cases, a conjunctival incision near the fornix was made depending on the tumor location as revealed by CT or MRI.

Accuracy of the posterior corneal elevation values of Pentacam HR from different reference surfaces in early ectasia diagnosis.

Purpose: Detecting the accuracy of various posterior elevation (PE) indices of Pentacam HR, and correlating them with some possibly related factors or parameters, in a cohort with early keratoconus (KC).

Methods: A cross sectional study that was conducted at Eye World Hospital, Egypt. One hundred and two corneas were enrolled, including two groups; group 1 (50 corneas) having forme fruste or early KC, and group 2 (52 corneas) for healthy controls.

Measurement of central corneal thickness using Orbscan 3, Pentacam HR and ultrasound pachymetry in normal eyes.

Purpose: To assess the agreement between Orbscan 3, Pentacam HR and ultrasound pachymetry (Palm Scan AP 2000) in measuring central corneal thickness.

Methods: Prospective observational cross-sectional study of ninety-two eyes of 48 patients with normal corneas was conducted. Central corneal thickness was measured via Pentacam HR, Orbscan 3 and ultrasound pachymetry.

Orbscan 3 Versus Pentacam HR: Evaluating the Possible Interchangeable Use of Various Parameters.

Purpose: Many topography/tomography devices are available, and their interchangeable use is frequently questioned. This study aimed to compare the analogous indices of Orbscan 3 and Pentacam HR to detect whether the interchangeable use of the 2 devices is feasible.

Methods: This retrospective study was conducted at Eye World Hospital, Giza, Egypt.

Unusually very late-onset new growth of intraocular retinoblastoma: A case report and review of literature.

Purpose: To report a patient who presented with a very late-onset new growth of intraocular retinoblastoma, which occurred 11 years after the initial combined treatment.

Observations: A 12-year-old monoophthalmic female patient presented with bilateral familial retinoblastoma showing new growth of intraocular tumor after 11 years of complete regression following combined local and systemic treatments. The new tumor growth was treated with diode laser transpupillary thermotherapy, ruthenium-106 plaque radiotherapy and adjuvant intravenous chemotherapy and the tumor regressed.

Subthreshold diode-laser micropulse photocoagulation as a primary and secondary line of treatment in management of diabetic macular edema.

Background: The purpose of this study was to evaluate subthreshold diode-laser micropulse (SDM) photocoagulation as a primary and secondary line of treatment for clinically significant diabetic macular edema (CSDME).

Methods: In this prospective nonrandomized case series, 220 cases of nonischemic CSDME were managed primarily and secondarily by SDM photocoagulation on a 15% duty cycle with a mean power of 828 mW and a spot size of 75-125 μm. SDM treatment was repeated at 3-4-month intervals if residual leakage was observed.

Secondary glaucoma as initial manifestation of uveal melanoma.

Purpose: Secondary glaucoma can be induced by a variety of local ocular problems. Intraocular tumors may initially present as secondary glaucoma.

Methods: 8 consecutive patients with secondary glaucoma were found to have uveal melanoma.

Retinoblastoma major review with updates on Middle East management protocols.

Many advances in the field of management of retinoblastoma emerged in the past few years. Patterns of presentation of retinoblastoma in the Middle East region differ from Western community. The use of enucleation as a radical method of eradicating advanced disease is not easily accepted by patient's family.

Management of lipid exudates in Coats disease by adjuvant intravitreal triamcinolone: effects and complications.

AIM To evaluate the role of intravitreal Triamcinolone (TA) in the early management of Coats disease. METHODS Retrospective, interventional case series. RESULTS 15 consecutive cases with Coats disease were managed with 4 mg/0.

Ocular surface tumors.

Tumors of the conjunctiva and cornea comprise a large and varied spectrum of conditions. These tumors are grouped into two major categories of congenital and acquired lesions. The acquired lesions are further subdivided based on origin of the mass into surface epithelial, mucoepidermoid, melanocytic, vascular, fibrous, neural, histiocytic, myxoid, myogenic, lipomatous, lymphoid, leukemic, metastatic and secondary tumors.

Ru106 brachytherapy for management of choroidal melanoma: do we need to adjust total dose according to the new NIST calibration measurement?

Purpose: To detect the need of adjusting the apical total dose according to the new NIST calibration measurement introduced by BEBIG Isotopen und Medizintechnik GmbH for the treatment of choroidal melanoma. As the total radiation dose should not be individualized depending on errors pf previous calibration but can be applicable if based on a radiosensitivity test that was able to predict the final response of tumor to radiation for each particular patient.

Patients And Methods: Twenty patients with choroidal melanomas were treated between November 2002 and July 2004 at "Suzanne Mubarak Eye Tumor Centre", National Eye centre Rod-EL Farag, Cairo, Egypt.