Publications by authors named "Iguosadolo Nosamiefan"
Article Synopsis
- Identifying various animal hosts involved in spill-over events of infectious diseases is essential for understanding how viruses like Lassa virus (LASV) are transmitted to humans and pose public health risks.
- Researchers conducted a study in southern Nigeria, screening domestic and non-domestic animals, including birds and lizards, to assess their potential as LASV reservoirs.
- Results showed lizards had the highest positivity rates for LASV, while cattle showed significant seropositivity, pointing to the need for further analysis of these animal hosts to inform strategies for managing Lassa fever transmission.
Article Synopsis
- The study focuses on the emergence and dissemination patterns of the SARS-CoV-2 B.1.1.318 and B.1.525 (Eta) variants in Nigeria and Africa, highlighting their significance for public health policies during a pandemic.
- By combining genomic and travel data, the research indicates that both variants originated from within Africa, with B.1.525 emerging specifically in Nigeria before spreading globally.
- The findings emphasize the importance of understanding regional connectivity and bidirectional transmission in Africa, revealing that the risks of virus importation between countries have been underestimated.
Article Synopsis
- A lot of money has been spent on studying the COVID-19 virus in Africa, leading to over 100,000 virus samples being analyzed to understand the spread of the disease.
- *More countries in Africa are now able to do these studies themselves, which helps them get results faster and keep a close watch on the virus.
- *To keep fighting COVID and other diseases, more funding and support for testing and research in Africa is really important for the future.
Article Synopsis
- The SARS-CoV-2 pandemic in Africa has varied significantly across countries, and its overall impact remains unclear.
- An analysis of 8,746 genomes from 33 African countries indicated that most outbreaks originated from Europe before international travel restrictions took effect.
- As the pandemic continued, increased movement and local transmission led to the emergence of several variants within Africa, emphasizing the need for a strong pandemic response on the continent to prevent becoming a source of new variants.
Background: Plasmodium falciparum malaria remains a major health challenge in Nigeria despite the global decline of its incidence and mortality rates. Although significant progress has been made in preventing the transmission of P. falciparum and controlling the spread of the infection, there is much to be done in the area of proper monitoring, surveillance of the parasite, investigating the population dynamics and drug resistance profiling of the parasite as these are important to its eventual eradication.
View Article and Find Full Text PDFDuring 2018, an unusual increase in Lassa fever cases occurred in Nigeria, raising concern among national and international public health agencies. We analyzed 220 Lassa virus genomes from infected patients, including 129 from the 2017-2018 transmission season, to understand the viral populations underpinning the increase. A total of 14 initial genomes from 2018 samples were generated at Redeemer's University in Nigeria, and the findings were shared with the Nigerian Center for Disease Control in real time.
View Article and Find Full Text PDFContainment limited the 2014 Nigerian Ebola virus (EBOV) disease outbreak to 20 reported cases and 8 fatalities. We present here clinical data and contact information for at least 19 case patients, and full-length EBOV genome sequences for 12 of the 20. The detailed contact data permits nearly complete reconstruction of the transmission tree for the outbreak.
View Article and Find Full Text PDFAs the intensity of malaria transmission has declined, Plasmodium falciparum parasite populations have displayed decreased clonal diversity resulting from the emergence of many parasites with common genetic signatures (CGS). We have monitored such CGS parasite clusters from 2006 to 2013 in Thiès, Senegal, using the molecular barcode. The first, and one of the largest observed clusters of CGS parasites, was present in 24% of clinical isolates in 2008, declined to 3.
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