Publications by authors named "Igor R L Barreto"
An Acad Bras Cienc
February 2018
Article Synopsis
- The paper investigates the trypanocidal activity of new carbohydrazide derivatives derived from a specific pyrazolo compound, focusing on their effectiveness against different forms of Trypanosoma cruzi.
- The study found that the four carbohydrazide derivatives exhibited varying levels of antiparasitic activity, suggesting that their chemical structures play a significant role in their effectiveness.
- Key factors influencing this activity include differences in lipophilicity and molecular volume, alongside their stereoelectronic properties and overall physical-chemical characteristics.
