Publications by authors named "Igor Moises Longo Snitcovsky"
Oral mucositis prevention by low-level laser therapy in head-and-neck cancer patients undergoing concurrent chemoradiotherapy: a phase III randomized study.
Aline Gouvêa de Lima Rosângela Correa Villar Gilberto de Castro Reynaldo Antequera Erlon Gil Igor Moisés Longo Snitcovsky
Int J Radiat Oncol Biol Phys
January 2012
Purpose: Oral mucositis is a major complication of concurrent chemoradiotherapy (CRT) in head-and-neck cancer patients. Low-level laser (LLL) therapy is a promising preventive therapy. We aimed to evaluate the efficacy of LLL therapy to decrease severe oral mucositis and its effect on RT interruptions.
View Article and Find Full Text PDFHigh-dose cisplatin concurrent to conventionally delivered radiotherapy is associated with unacceptable toxicity in unresectable, non-metastatic stage IV head and neck squamous cell carcinoma.
Gilberto de Castro Igor Moisés Longo Snitcovsky Eloísa Maria Mello Santiago Gebrim Glauber Moreira Leitão Wladimir Nadalin
Eur Arch Otorhinolaryngol
December 2007
Article Synopsis
- - Unresectable head and neck squamous cell carcinoma (HNSCC) includes a diverse group of patients, specifically in stages III and IV, and this study investigated the feasibility of a specific treatment regime involving cisplatin and radiotherapy for stage IV patients.
- - A total of 30 patients participated in the study, where they received a combination of 70 Gy radiation and cisplatin, resulting in an overall response rate of 60%, with some patients achieving complete or partial tumor responses.
- - The treatment was associated with significant side effects, including toxicities affecting 26 patients and three deaths, with median progression-free survival of 8 months and overall survival of 17.3 months noted, indicating challenges in administering