Study of structural and biochemical changes in the muscular tissue of the oesophagus for solving the problem of diagnosing the prescription of death coming.

Unlabelled: The modern practice and tactics of forensic medical diagnosis require scientific substantiation of informative diagnostic criteria for assessing the prescription of death coming (PDC), first of all during the early postmortem period (PMP).

Aim: The aim of the study was an evaluation of the concentration changes of biochemical markers (BCM) in muscular tissue (MT) of the oesophagus during the early postmortem period.

Materials And Methods: MT of the oesophagus within the period of 3-13 hours after the coming of death was studied on 30 human corpses.

Metabolic restriction of cancer cells in vitro causes karyotype contraction--an indicator of cancer promotion?

The metabolism of cultured cancer cells is stimulated by 21% oxygen and generous nutrition, while real tumors grow in oxygen and nutrient-restricted environments. The effect of these contrasted conditions was studied in five hyperploid (54-69) cancer cell lines. When grown under anoxia and in the presence of antioxidant metabolic restrictors, the cell lines quickly reverted to almost normal chromosome numbers (47-49).