The aim of the present study was to characterize the expression of the pancreatic beta cell antigen family with molecular masses of 64 to 69 kDa [p(64-69)]. This antigen family was detected by immunoreactivity with biotinylated monoclonal antibody (Mab) ICA-1, and Mab against insulin. The molecular masses of the antigens affinity-purified from islet cell lysates by ICA-1 were 64, 67, and 69 kDa.
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