Publications by authors named "Ignazio Alessio Gueli"
Article Synopsis
- * Traditional prevention methods primarily involve lifestyle changes and medication, but integrating advanced imaging techniques like ultrasound and MRI can enhance early detection and monitoring of cardiovascular issues.
- * This review explores how these innovative imaging technologies can contribute to personalized prevention strategies and improve our overall understanding of cardiovascular health, ultimately aiming to reshape preventive care in cardiology.
Cardiac magnetic resonance represents the gold standard imaging technique to assess cardiac volumes, wall thickness, mass, and systolic function but also to provide noninvasive myocardial tissue characterization across almost all cardiac diseases. In patients with cardiac amyloidosis, increased wall thickness of all heart chambers, a mildly reduced ejection fraction and occasionally pleural and pericardial effusion are the characteristic morphologic anomalies. The typical pattern after contrast injection is represented by diffuse areas of late gadolinium enhancement, which can be focal and patchy in very early stages, circumferential, and subendocardial in intermediate stages or even diffuse transmural in more advanced stages.
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- This study distinguishes between nondilated left ventricular cardiomyopathy (NDLVC) and dilated cardiomyopathy (DCM) by using cardiac magnetic resonance (CMR) and genetic testing on 462 patients across four centers.
- Findings showed that NDLVC patients had better heart function and a higher prevalence of specific genetic variants compared to those with DCM, highlighting significant differences in their conditions.
- The presence of septal late gadolinium enhancement and other factors like LV dilatation, age, and arrhythmias were identified as strong predictors for serious cardiac events, such as sudden cardiac death.
We derived reference values of left-ventricular (LV) and right-ventricular (RV) strain parameters in a cohort of 100 healthy subjects by feature tracking cardiac magnetic resonance (FT-CMR). Global and regional strain values were calculated for the LV; circumferential and radial strain parameters were derived from the short-axis (SAX) stack, while longitudinal and radial strain parameters were assessed in three long-axis (LAX) views. Only global longitudinal strain (GLS) was calculated for the RV.
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