[Comparative analysis of the microbiological stability of modern polymers for the manufacture of removable prostheses].

Objective: The aim of the study is to study the degree of adhesion of reference strains of microorganisms to the surface of modern polymer materials for the manufacture of removable prostheses.

Materials And Methods: The primary and residual microbial adhesion of 4 types of polymers was studied: acrylic polymer (Villacryl H Plus), monomerless polymer (Vertex ThermoSens), photopolymers for additive manufacturing (Harz Labs Dental Denture Base, Harz Labs Dental Sand). , , , and were used as reference strains.

Diastolic deceleration area in the fetal MCA: a new Doppler parameter.

Doppler velocimetry has been widely used throughout the years as a valuable tool in the follow-up and prognosis of various pregnancy complications. Numerous Doppler indices have been introduced to qualitatively describe fetal blood flow. Currently, the Pulsatility index (PI) is the most widely used index for this purpose.

Myasthenia gravis and covid-19 in pregnancy: a review of the literature and case series report.

Objectives: The aim of our study was to investigate the interrelations of symptoms, clinical outcomes and treatment regimens in pregnant women, diagnosed with myasthenia gravis and superimposed COVID-19 infection.

Methods: We conducted an observational retrospective study between August, 2020 and July, 2021. Five patients with preexisting MG and superimposed COVID- infection were included in our study.

Spectral and Texture Properties of Hydrophobic Aerogel Powders Obtained from Room Temperature Drying.

Attenuated Total Reflectance Infrared (ATR-IR) spectroscopy and texture measurements based on nitrogen adsorption-desorption isotherms are combined to characterize silica aerogel granules with different degrees of hydrophobicity. The aerogels were prepared from tetraethoxysilane via a room temperature hydrolysis-gelation process, solvent exchange, hydrophobization, and drying at subcritical conditions. The dependencies between the texture properties, pore architectures, surface fractal dimensions, and degree of hydrophobicity of the samples are extracted from the ATR-IR spectra and the adsorption-desorption isotherms.

Thiourea Modified Doxorubicin: A Perspective pH-Sensitive Prodrug.

A novel approach to the synthesis of pH-sensitive prodrugs has been proposed: thiourea drug modification. Resulting prodrugs can release the cytotoxic agent and the biologically active 2-thiohydantoin in the acidic environment of tumor cells. The concept of acid-catalyzed cyclization of thioureas to 2-thiohydantoins has been proven using a FRET model.

Quantitative cardiotocography to improve fetal assessment during labor: a preliminary randomized controlled trial.

Objective: To evaluate the effectiveness of a computerized decision support system, referred to as "quantitative cardiotocography" (qCTG), to reduce adverse birth outcomes compared to conventional CTG with fetal blood sampling.

Study Design: A preliminary parallel randomized control trial in a tertiary maternity hospital (Sofia, Bulgaria) was conducted with a sample size of 360 women per trial arm (N=720). Women in labor were recruited between March 2008 and March 2011.

[EVALUATION OF INCIDENCE OF POSTPARTUM OCCULT ANAL SPHINCTER INJURIES BY ENDOANAL ULTRASONOGRAPHY.].

The estimated overall risk of intrapartum damage of the anal sphincter (IUAS) is 1% of all vaginal births. The so called "occult" anal sphincter injuries (defects of the anal sphincter established by endoanal ultrasonography - OASIS) occur in 33% of primiparous women after vaginal birth. The most logical explanation for OASIS is that they are either completely missed or detected, but not mentioned in the patient's documentation, or erroneously classified as a low grade tear.

[INFLUENCE OF DIANATALO OBSTETRIC GEL ON THE LENGTH OF SECOND STAGE OF LABOR.].

One of the risk factors for the occurrence of occult anal sphincter injuries (OASIS) and pelvic floordamage is the increased duration of the second stage of labor; leading to a relatively high incidence of perineal trauma, which in the majority of cases remains unrecognized. If we can decrease the duration of second stage of labor we could also expect a statistically significant decrease the incidence of OASIS in clinical practice. Purpose and Goals To identify changes in the length of the second slage of labor fater adminidtration of Dianatal® obstetric gel.

[RISK FACTORS FOR POSTPARTUM OCCULT INJURIES OF THE ANAL SPHINCTER.].

introduction The overall risk of intrapartum damage the anal sphincter (IUAS) is 1% of all vaginal births. In contrast, the so-called "occult" anal sphincter injuries (OASIS) (defects esablished by endoanal ultrasonography) occur in 33% of primiparous women after vaginal birth. Identifying the most common risk factors for OASIS can be the basis for selecting high-risk patients.

[Indirect standard cardiotocography plus fetal blood sampling versus indirect quantitative cardiotocography--a randomized comparative study in intrapartum monitoring].

Introduction: In previous papers we proposed ways to improve the diagnostic potential of the "quantitative cardiotocography" computer method, which allowed us to introduce clinical practice guidelines. Using these guidelines we aim to evaluate the effectiveness of quantitative cardiotocography (qCTG) as compared to standard cardiotocography (CTG) and, if necessary fetal blood sampling (FBS).

Material And Methods: The prospective study involves 220 pregnant women divided randomly into two groups.

[Structure and function of the cardiotocographic score (CTG-score) calculated by the "quantitative cardiotocography" computer method. Determining the significance of its components for the accuracy of the estimates for the ph of the fetus].

Introduction: In the last three years "quantitative cardiotocography" has become the main method for fetal monitoring during late pregnancy and birth in Sheynovo hospital - Sofia, Bulgaria. Our previous studies presented opportunities for increasing the diagnostic potential of the methodology. In this paper we offer a new approach to further improve the accuracy of prognostic values for fetal pH during labor.

["Quantitative cardiotocography"--clinical practice guideline].

Introduction: The "quantitative cardiotocography" method provides important information about the condition of the fetus during labor, non-invasively and in real time. Since the forecast pH-results are being updated every 5 (five) minutes, significant differences in the readings for pH can be observed. In certain cases this can hamper the evaluation of fetal condition and lead to contradictions.

[A comparative study of the prognostic pH values of the fetus in utero, generated by the "quantitative cardiotocography" computer method, and the actual pH values measured immediately after delivery].

Introduction: The presented methodology for quantitative evaluation of the cardiotocographic (CTG) findings unconditionally provides essential opportunities for improving the diagnostic potential in modern obstetric practice. Current literature data concerning the clinical application of this method are scarce. Credible clinical trials are needed to determine what is the correlation between estimated and actual values of the studied variables.

[Quantitative cardiotocography].

Unlabelled: Cardiotocography (CTG) is an up-to-date practical method for fetal surveillance during pregnancy and labor. More precise reading of the CTG data is possible with the use of some fetal acid-base parameters, taken from the umbilical artery (UA). Unfortunately, invasive procedures like fetal scalp blood sampling and/or cordocentesis are required to obtain these results.

Escherichia coli inorganic pyrophosphatase: site-directed mutagenesis of the metal binding sites.

Aspartic acids 65, 67, 70, 97 and 102 in the inorganic pyrophosphatase of Escherichia coli, identified as evolutionarily conserved residues of the active site, have been replaced by asparagine. Each mutation was found to decrease the k(app) value by approx. 2-3 orders of magnitude.

[Antibiotic prevention and treatment in cesarean section].

The aim of the authors ia to study the role of antibiotic prophylaxis in cesarean section for prevention of infectious complications during puerperium. 443 deliveries were studied, which took place by cesarean section at the obstetric clinic of the Higher Medical Institute in the town of Pleven for a 2-year period. One antibiotic was administered in 96 women (21.

[Diagnostic problems in extrauterine pregnancy].

The aim of the authors was to investigate reliability of method, used by them, for diagnosis of extrauterine pregnancy EP (EP). 123 women with admission diagnosis: obs. graviditas extrauterine were studied retrospectively.

[Immunogenic activity of synthetic brucellosis antigens].

Experimental data obtained in this investigation indicate that the conjugation of Brucella protective antigen with a polymer carrier essentially increase the immunogenic properties of the antigen. Synthesized vaccinal preparations can be of interest for practical use, as these preparations, while inducing the development of intense immunity, do not impede the diagnosis of brucellosis by serological reactions. The comparative study of the conjugates of Brucella antigen with different carriers shows that the conjugated preparation obtained on the basis of modified dextran possesses high protective potency, which makes it possible to regard this carrier as very promising for further use.