Publications by authors named "Ignatius K P Cheng"

Background/purpose: Dyslipidemia is common in liver transplant recipients. This retrospective study investigates whether donors play a role.

Methods: Prospectively collected data of donors and recipients of deceased-donor liver transplantation (DDLT) and living-donor liver transplantation (LDLT) were reviewed.

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Gastrointestinal stromal tumors (GISTs) are the most common primary mesenchymal gastrointestinal neoplasms. However, GISTs occurring in kidney transplant recipients, including their treatment and outcome, are rarely described in literature. We hereby report two kidney transplant recipients with GISTs.

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Background: The shortage of cadaveric kidneys for renal transplantation is a particularly problematic situation in the locality of Hong Kong. Kidneys from spousal donors are therefore increasingly being used for transplantation. This study was undertaken to evaluate the outcome of spousal donor transplant recipients in comparison with that of genetically related living donor (LRD) allograft recipients.

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Article Synopsis
  • Management of acute hepatitis C virus (HCV) infection post-renal transplantation remains debated due to potential risks involved with interferon treatment.
  • Four renal transplant recipients with acute HCV were treated with a combination of interferon-alpha 2b and ribavirin, resulting in successful viral suppression in three patients after 48 weeks.
  • The most common side effect was dose-dependent hemolysis, but none experienced kidney graft dysfunction, suggesting this treatment approach may be viable for selected patients.
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Hepatitis B surface antigen (HBsAg)-positive kidney transplant recipients have increased liver-related mortality. The impact of lamivudine treatment on patient survival, the optimal time to start treatment, and the feasibility of discontinuing treatment have not been determined. This study examined these issues with a novel management protocol.

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Unlabelled: Percutaneous renal biopsy is a useful diagnostic procedure for many renal diseases. The experience with ultrasound-guided percutaneous renal biopsy from a single operator was reviewed to identify the possible risk factors of complications after the procedure.

Methods And Results: From 1995 to 1998, 203 biopsies (141 on native kidneys with 14G needles, 62 on transplant kidneys with 18G needles) were performed on 186 individuals as clinically indicated.

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