Publications by authors named "Ignacio Reyes Moreno"
Diagnostic Algorithm for Intracranial Lesions in the Emergency Department: Effectiveness of the Relative Brain Volume and Hounsfield Unit Value Measured by Perfusion Tomography.
Cureus
June 2024
Article Synopsis
- Early treatment of intracranial lesions is crucial but challenging to differentiate, as each type requires different treatment strategies; Cerebral computed tomography perfusion (CTP) imaging is effective in visualizing and quantifying brain lesions' vascularity.
- This study evaluated the effectiveness of Hounsfield units (HU) and CTP in distinguishing various intracranial space-occupying lesions over a five-year period, involving 244 patients with conditions including glioblastomas, primary central nervous system lymphoma, metastases, and abscesses.
- Results indicated that combining rCBV and HU measurements enhances diagnostic accuracy for differentiating lesions, and the simplicity and availability of CTP make it a valuable tool for diagnosing and managing brain tumors.
Background: Glioblastoma is one of the most common brain tumors in adult populations, usually carrying a poor prognosis. While several studies have researched the impact of anti-angiogenic therapies, especially anti-VEFG treatments in glioblastoma, few have attempted to assess its progress using imaging studies.
Purpose: We attempted to analyze whether relative cerebral blood volume (rCBV) from dynamic susceptibility-weighted contrast-enhanced MRI (DSC-MRI) could predict response in patients with glioblastoma undergoing Bevacizumab (BVZ) treatment.
Background: Meningiomas represent 30% of primary intracranial tumors. The current incidence is up to 4.5 cases per 100,000 habitants worldwide.
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- Glioblastoma (GB) is a highly aggressive brain cancer with poor prognosis, and this study aims to analyze 17 years of therapeutic and prognostic experiences in Mexico.
- A retrospective study from 2000 to 2017 involved 137 patients; most received various combinations of treatments, including stereotactic radiotherapy, Temozolomide (TMZ), and Bevacizumab (BVZ).
- The findings revealed that patients receiving the combination of RT/TMZ/BVZ had significantly better progression-free survival and overall survival compared to other treatment groups, emphasizing the need for further research on biological factors influencing outcomes in this population.
The Comparative Treatment of Intraventricular Chemotherapy by Ommaya Reservoir vs. Lumbar Puncture in Patients With Leptomeningeal Carcinomatosis.
Front Oncol
November 2018
Leptomeningeal Carcinomatosis (LCM) represents a state of systemic malignant disease with poor prognosis. The purpose of this study is to compare overall survival (OS) between intraventricular chemotherapy through Ommaya reservoir (OR) and chemotherapy through lumbar puncture (LP) in LCM. Forty adult patients with LCM were included.
View Article and Find Full Text PDFBackground: Central nervous system (CNS) tumors are a group of neoplasms that originate from various cells in the CNS. The increasing incidence and prevalence of this type of tumor in developing countries are striking; however, there are few current studies in Latin America including Mexico estimating the impact of these pathological entities on the general population.
Objective: The objective of the study was to study the characteristics of primary CNS tumors over a period of 52 years.
Article Synopsis
- Hemifacial spasm is a condition marked by involuntary facial contractions, more common in females and the left side of the face, with treatment options including medication, botulinum toxin, and microvascular decompression.
- A study analyzed 116 microvascular decompression surgeries in 88 patients over 10 years, revealing that 70.45% experienced excellent immediate results, and 81.82% maintained excellent long-term outcomes despite some complications such as temporary facial palsy.
- While medical treatments and botulinum toxin provide temporary relief, microvascular decompression is favored for its minimally invasive nature and superior long-term efficacy.