Increased functional connectivity patterns in mild Alzheimer's disease: A rsfMRI study.

Background: Alzheimer's disease (AD) is the most common age-related neurodegenerative disorder. In view of our rapidly aging population, there is an urgent need to identify Alzheimer's disease (AD) at an early stage. A potential way to do so is by assessing the functional connectivity (FC), i.

Non-linear Functional Brain Co-activations in Short-Term Memory Distortion Tasks.

Recent works shed light on the neural correlates of true and false recognition and the influence of time of day on cognitive performance. The current study aimed to investigate the modulation of the false memory formation by the time of day using a non-linear correlation analysis originally designed for fMRI resting-state data. Fifty-four young and healthy participants (32 females, mean age: 24.

Revisiting Nonlinear Functional Brain Co-activations: Directed, Dynamic, and Delayed.

The center stage of neuro-imaging is currently occupied by studies of functional correlations between brain regions. These correlations define the brain functional networks, which are the most frequently used framework to represent and interpret a variety of experimental findings. In the previous study, we first demonstrated that the relatively stronger blood oxygenated level dependent (BOLD) activations contain most of the information relevant to understand functional connectivity, and subsequent work confirmed that a large compression of the original signals can be obtained without significant loss of information.

Psychological Distress in Erectile Dysfunction: The Moderating Role of Attachment.

Introduction: In clinical consultations, men with erectile dysfunction do not always express personal, sexual, and interpersonal concerns.

Aim: We explore whether the attenuated impact of erectile dysfunction may be explained by a regulation of negative affect that causes activation of the attachment system.

Methods: The study sample consisted of 69 men diagnosed with erectile dysfunction, mean (SD) age 56 (10.

Using Deep Learning and Resting-State fMRI to Classify Chronic Pain Conditions.

Chronic pain is known as a complex disease due to its comorbidities with other symptoms and the lack of effective treatments. As a consequence, chronic pain seems to be under-diagnosed in more than 75% of patients. At the same time, the advance in brain imaging, the popularization of machine learning techniques and the development of new diagnostic tools based on these technologies have shown that these tools could be an option in supporting decision-making of healthcare professionals.

Experience-dependent neuroplasticity in trained musicians modulates the effects of chronic pain on insula-based networks - A resting-state fMRI study.

Recent resting-state fMRI studies associated extensive musical training with increased insula-based connectivity in large-scale networks involved in salience, emotion, and higher-order cognitive processes. Similar changes have also been found in chronic pain patients, suggesting that both types of experiences can have comparable effects on insula circuitries. Based on these observations, the current study asked the question whether, and if so in what way, different forms of experience-dependent neuroplasticity may interact.

Power Spectral Density and Functional Connectivity Changes due to a Sensorimotor Neurofeedback Training: A Preliminary Study.

Neurofeedback is a form of neuromodulation based on learning to modify some aspects of cortical activity. Sensorimotor rhythm (SMR) oscillation is one of the most used frequency bands in neurofeedback. Several studies have shown that subjects can learn to modulate SMR power to control output devices, but little is known about possible related changes in brain networks.

Insula-based networks in professional musicians: Evidence for increased functional connectivity during resting state fMRI.

Despite considerable research on experience-dependent neuroplasticity in professional musicians, detailed understanding of an involvement of the insula is only now beginning to emerge. We investigated the effects of musical training on intrinsic insula-based connectivity in professional classical musicians relative to nonmusicians using resting-state functional MRI. Following a tripartite scheme of insula subdivisions, coactivation profiles were analyzed for the posterior, ventral anterior, and dorsal anterior insula in both hemispheres.

Altered Dynamic of EEG Oscillations in Fibromyalgia Patients at Rest.

Objective: Previous fMRI findings have shown that chronic pain patients display an altered activation and functional connectivity of the pain network. The aim of the present study was to analyze EEG dynamics in fibromyalgia patients (n = 20) and pain-free controls (n = 18) at rest.

Methods: Spectral power density, source current density, and intra- and inter-hemispheric coherence were analyzed from 64 EEG channels during 5-minutes eyes-closed rest.

Are physiotherapists reliable proxies for the recognition of pain in individuals with cerebral palsy? A cross sectional study.

Background: Pain is an important problem for individuals with cerebral palsy (CP). In addition to pain associated to the pathology, individuals with CP are often exposed to physiotherapy procedures which may cause or relieve pain.

Objective: The major aim of this study was to compare pain ratings self-reported by individuals with cerebral palsy and ratings about pain in others provided by their physiotherapists.

Altered corticomuscular coherence elicited by paced isotonic contractions in individuals with cerebral palsy: a case-control study.

The purpose of the study was to analyze corticomuscular coherence during planning and execution of simple hand movements in individuals with cerebral palsy (CP) and healthy controls (HC). Fourteen individuals with CP and 15 HC performed voluntary paced movements (opening and closing the fist) in response to a warning signal. Simultaneous scalp EEG and surface EMG of extensor carpi radialis brevis were recorded during 15 isotonic contractions.

Antecedent events as predictive variables for behavioral function.

Challenging behavior is one of the largest barriers to ensuring that people with intellectual disabilities (ID) are able to participate in the community. These difficulties have become one of the main causes of social exclusion. The research into and treatment of challenging behavior has usually involved the identification of its function and the manipulation of the events or environmental conditions that influence its occurrence (antecedent variables).

Agonistic strategies and spatial distribution in captive sooty mangabeys (Cercocebus atys).

The aim of this article is to study the relationship between the dominance hierarchy and the spatial distribution of a group of captive sooty mangabeys (Cercocebus atys). The analysis of the spatial distribution of individuals in relation to their rank in the dominance hierarchy showed a clear linear hierarchy in which the dominant individual was located in central positions with regard to the rest of the group members. The large open enclosure where the group was living allowed them to adopt a high-risk agonistic strategy in which individuals attacked other individuals whose rank was significantly different from their own.

Altered psychophysiological responses to the view of others' pain and anger faces in fibromyalgia patients.

Unlabelled: Facial expression provides information for an accurate estimation of others' pain. Nevertheless, little is known about psychophysiological responses to pain faces in chronic pain. Event-related potentials and brain oscillations, corrugator activity, and heart rate were recorded in 20 fibromyalgia patients and 20 pain-free controls when viewing pain, anger, happy, and neutral faces.

RETRACTED: Questions About Behavioral Function (QABF): adaptation and validation of the Spanish version.

This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy).

Somatosensory activity modulation during observation of other's pain and touch.

We examined whether somatosensory activity could be modulated by the observation of bodily experiences. For this purpose, somatosensory-evoked potentials elicited by non-painful stimulation were recorded when subjects were viewing a hand penetrated by a needle, touched by a cotton swab or at resting without stimulation. Participants were instructed to adopt an egocentric perspective when viewing the videos and to rate pain intensity and unpleasantness supposedly experienced by the model, as well as the unpleasantness induced by the video clips.

Disrupted functional connectivity of the pain network in fibromyalgia.

Objective: To investigate the impact of chronic pain on brain dynamics at rest.

Methods: Functional connectivity was examined in patients with fibromyalgia (FM) (n = 9) and healthy controls (n = 11) by calculating partial correlations between low-frequency blood oxygen level-dependent fluctuations extracted from 15 brain regions.

Results: Patients with FM had more positive and negative correlations within the pain network than healthy controls.

Age-related changes of pain experience in cerebral palsy and healthy individuals.

Objective:   Pain is a serious problem for many individuals with cerebral palsy (CP). Pain and injury in early life may cause long-term changes in somatosensory and pain processing. Nevertheless, no information exists regarding the influence of age on pain reports and touch sensitivity among persons with CP or the influence of age on the quality of life in individuals with CP.

Modular organization of brain resting state networks in chronic back pain patients.

Recent work on functional magnetic resonance imaging large-scale brain networks under resting conditions demonstrated its potential to evaluate the integrity of brain function under normal and pathological conditions. A similar approach is used in this work to study a group of chronic back pain patients and healthy controls to determine the impact of long enduring pain over brain dynamics. Correlation networks were constructed from the mutual partial correlations of brain activity's time series selected from ninety regions using a well validated brain parcellation atlas.