Publications by authors named "Ignacio Basurte-Villamor"

Tobacco smoking is the leading cause of disability and preventable deaths worldwide, but it should be differentiated from tobacco use disorder, which is, according to the Diagnostic and Statistical Manual of Mental Disorders, a mental disorder. The rapid delivery of nicotine to the brain activates acetylcholine receptors and stimulates the release of dopamine, both systems implicated in other mental disorders. Rates of tobacco use disorder are much higher among people suffering from other mental disorders and these patients find it more difficult to quit.

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Schizophrenia is often associated with substance use disorders, particularly cannabis use disorder (CUD). However, treatments frequently fail to address both conditions simultaneously. This study aimed to evaluate the antipsychotic effectiveness of cariprazine in patients with both schizophrenia and CUD in a real-world setting.

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Article Synopsis
  • * A study of 116 patients at a specialized treatment center used questionnaires to confirm GD and assess for co-occurring issues, revealing high rates of ADHD, depression, anxiety, and substance use disorders, along with impulsive behaviors.
  • * The analysis identified two clinical profiles based on severity: one with a greater complexity of mental disorders and higher impulsivity, suggesting that impulsiveness may be a key vulnerability factor for developing GD.
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Background: Limited studies have evaluated the effectiveness of vortioxetine in real-world settings, and none of them has involved patients with dual depression (major depressive disorder [MDD] and substance use disorder [SUD]). The objective of the study was to describe the effectiveness of vortioxetine in clinical practice and determine its effect on affective symptoms, cognitive function, quality of life, and substance use in patients with MDD and SUD.

Methods: Post-authorization, retrospective, multicenter, descriptive, and observational study in 80 patients with MDD and SUD receiving a maintenance treatment with vortioxetine for six months between January 2017 and April 2021.

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Several behaviors, including compulsive gambling, have been considered non-substance-related addictive disorders. Categorical mental disorders (e.g.

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A randomized, 1-year follow-up study comparing LAI aripiprazole with LAI paliperidone in patients with psychosis, mostly schizophrenia, and SUD reported a large effect of the change from baseline in the CGI severity score, from 5.9 to 2.4 for LAI aripiprazole and from 5.

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Aim: To evaluate the efficacy and impact of long-acting injectable (LAI) aripiprazole in patients with schizophrenia with a coexisting substance use disorder (SUD).

Patients And Methods: A multicenter, observational, descriptive and retrospective study was conducted in patients with a DSM-5 diagnosis of schizophrenia who had a coexisting SUD and were treated with LAI-aripiprazole. Disease severity was evaluated with the Clinical Global Impression (CGI) severity scale for schizophrenia, daily functioning and disability were evaluated with the World Health Organisation Disability Assessment Scale (WHODAS-2.

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Article Synopsis
  • * A study involving 89 ED patients utilized various assessment scales to distinguish between those with and without ADHD symptoms, revealing differences in the severity and nature of their eating disorders.
  • * Findings suggest that patients with both ED and ADHD symptoms experience more severe eating disorder symptoms, higher levels of impulsivity, and a diminished quality of life, underscoring the need for ADHD assessment in ED treatment.
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Objectives: To assess the knowledge of health professionals attending patients with dual disorders about specific resources for patients with this condition in different Spanish regions.

Methods: Observational, cross-sectional, multicenter study to compare the perceptions of healthcare professionals (n=659) with reality regarding specific resources available for patients with dual disorders in Spain. The professionals completed an online questionnaire.

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Objective: Since provision of integrated services for patients with dual pathology or dual disorders (coexistence of an addictive disorder and another mental health disorder) is an important challenge in mental health, this study assessed health care professionals' perceptions and knowledge of the current state of specific resources for patients with dual pathology in Spain.

Methods: We conducted a national survey of health care professionals seeing patients with dual pathology in treatment facilities throughout Spain. Participants completed a specific online questionnaire about the needs of and available resources for patients with dual pathology.

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Background: Since provision of integrated services for patients with dual pathology or dual disorders (coexistence of an addictive disorder and other psychiatric disorders) constitutes an important challenge, this study compared the perceptions of health-care professionals with the existing, current state of specific resources for patients with dual pathology in Spain.

Methods: Epidemiological, observational, cross-sectional, multicenter study with a large, representative sample of health care professionals attending patients with dual pathology in treatment resources throughout Spain. Participants completed a specifically designed ad-hoc on-line questionnaire about their perceptions on the existence of available resources and treatment needs for patients with dual pathology.

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Aim: To evaluate retrospectively the comorbidity of mental and addictive disorders in community mental health and substance misuse services in Madrid.

Methods: The medical records of 400 patients from mental health and substance misuse services in Madrid were evaluated. Records were examined for the last 20 patients from each service unit.

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Article Synopsis
  • * This study analyzed data from 30,965 individuals under 18 years old receiving outpatient psychiatric care between 1980 and 2007 to explore the correlation between parental age and various ICD-10 diagnoses.
  • * Results indicated that both maternal and paternal ages were higher in subjects diagnosed with mental retardation, with a notable increase in the risk of psychotic disorders specifically associated with advancing maternal age, while paternal age did not show the same correlation.
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  • The European Commission prioritizes mental health, highlighting the need for studies on the use and costs of mental health services to enhance resource planning and efficiency.* -
  • Data was analyzed from 22,859 patients receiving psychiatric care in Spain (2000-2004), focusing on two groups that accounted for most costs: medium (4,212 patients) and high cost (236 patients) groups, utilizing both univariate and multivariate statistical methods.* -
  • Findings revealed that 19.4% of patients generated 80% of mental healthcare costs, with high costs linked to factors such as age (0-14 years), permanent disability, and specific mental health diagnoses like schizophrenia and substance use disorders.*
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Article Synopsis
  • Psychiatric disorders contribute significantly to global disease burden, and the study aims to assess the long-term stability of common psychiatric diagnoses across different clinical environments.
  • The research analyzed data from over 34,000 patients in a Spanish hospital, focusing on 10,025 adults who underwent multiple evaluations in various settings.
  • Results showed poor stability in psychiatric diagnoses, with schizophrenia being the most consistent at 70% and specific personality disorders the least at 29%, highlighting concerns about current diagnostic practices.
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Background: The aim of this study is to investigate differences among immigrants and natives regarding access and pathways to psychiatric care, psychiatric admission rates, length of stay, continuity of care, and main diagnoses.

Methods: Psychiatric emergency visits (1511) and hospitalizations (410) were registered in a Spanish Hospital with a catchment area of 280 000 people (19.3% immigrants) during the year 2003.

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