Publications by authors named "Ignacio Adiego Calvo"
Objective: To explore the predictive value of serum human epididymis protein 4 (HE4) marker in the preoperative prediction of the risk of advanced disease in the endometrioid subtype of endometrial cancer, and its association with poor prognostic factors. In addition, a cut-off value of HE4 was defined to classify patients according to these results.
Methods: Prospective and multicenter cohort analytical pilot study of patients operated for endometrial cancer at the Miguel Servet University Hospital of Zaragoza (Spain) and the Complejo Universitario of León (Spain) from January 2017 to May 2019.
Article Synopsis
- Persistent right umbilical vein (PRUV) is a vascular anomaly that can lead to various congenital defects in fetuses, and this study differentiates between its intrahepatic (I-PRUV, better prognosis) and extrahepatic variants (worse prognosis).
- A multicenter study conducted from 2003 to 2013 analyzed 56 cases of I-PRUV against 4,050 singleton pregnancies without risk factors for congenital malformations.
- The findings showed a significant association between I-PRUV and congenital malformations, particularly in the genitourinary system, with an overall malformation rate of 17.9%, while isolated I-PRUV did not indicate a worse prognosis.