Unique presentation of acute neuro-Behçet's disease involving a cytotoxic oedema core surrounded by vasogenic oedema.

A 53-year-old woman with recurrent stomatitis, genital ulcers, and folliculitis was admitted to Tokyo Medical University Hospital after experiencing visual disturbances for the past 2 weeks and a nonthrobbing headache for the past 3 days. She had also developed numbness in her left extremities. An ophthalmological examination revealed inflammatory changes in the eye.

On the effectiveness of a contrastive cascade graph learning framework: The power of synthetic cascade data.

Analyzing the dynamics of information diffusion cascades and accurately predicting their behavior holds significant importance in various applications. In this paper, we concentrate specifically on a recently introduced contrastive cascade graph learning framework, for the task of predicting cascade popularity. This framework follows a pre-training and fine-tuning paradigm to address cascade prediction tasks.

Two Cases of Wells Syndrome with Marked Swelling in the Hands.

Wells syndrome or eosinophilic cellulitis is an idiopathic inflammatory dermatitis characterized by a benign but recurrent evolution. It often causes edematous urticarial plaques on the extremities. Herein, we report two rare cases of Wells syndrome with marked swelling in the hands.

Upconverted emission-driven photothermal conversion with gold nanospheres based on triplet-triplet annihilation.

Low-energy visible light was converted into heat energy through the excitation of the localized surface plasmon resonance of gold nanospheres excited by upconverted emission based on triplet-triplet annihilation of organic molecules. This system allows easy tuning of absorption/emission wavelengths, which is difficult with conventional photothermal conversion using rare-earth elements.

Plasmonic Silver Nanoprism-Induced Emissive Mode Control between Fluorescence and Phosphorescence of a Phosphorescent Palladium Porphyrin Derivative.

We have succeeded in significantly enhancing fluorescence from intrinsically phosphorescent palladium octaethylporphyrin (Pd-porphyrin) that has an intersystem crossing efficiency of ∼1 by using silver nanoprisms (AgPRs). This was achieved by controlling the wavelength of the localized surface plasmon (LSP) resonance of AgPRs and the distance between the Pd-porphyrin molecules and the AgPR surfaces. In addition to enhancing phosphorescence by spectrally overlapping the phosphorescence band with the LSP resonance band, tuning the LSP wavelength to approximately 520 nm led to the appearance of a new emission band around the wavelength corresponding to the fluorescent radiation.

Dramatic effect of hydroxychloroquine on lupus alopecia.

Lupus alopecia is usually difficult to treat. We report a case of a 40-year-old woman with Sjögren's syndrome and atopic dermatitis who presented with discoid lupus erythematosus on the forearms and lupus erythematosus profundus with alopecia involving the scalp. A biopsy specimen taken from the discoid lupus erythematosus lesion on the forearm further exhibited a xanthomatous reaction, which however was not detected in another specimen from the lupus erythematosus profundus on the scalp.

Development of Plasmonic CuO/Cu Composite Arrays as Visible- and Near-Infrared-Light-Driven Plasmonic Photocatalysts.

We describe efficient visible- and near-infrared (vis/NIR) light-driven photocatalytic properties of hybrids of CuO and plasmonic Cu arrays. The CuO/Cu arrays were prepared simply by allowing a Cu half-shell array to stand in an oxygen atmosphere for 3 h, which was prepared by depositing Cu on two-dimensional colloidal crystals with a diameter of 543 or 224 nm. The localized surface plasmon resonances (LSPRs) of the arrays were strongly excited at 866 and 626 nm, respectively, at which the imaginary part of the dielectric function of Cu is small.

Properties and crystal structure of methylenetetrahydrofolate reductase from Thermus thermophilus HB8.

Background: Methylenetetrahydrofolate reductase (MTHFR) is one of the enzymes involved in homocysteine metabolism. Despite considerable genetic and clinical attention, the reaction mechanism and regulation of this enzyme are not fully understood because of difficult production and poor stability. While recombinant enzymes from thermophilic organisms are often stable and easy to prepare, properties of thermostable MTHFRs have not yet been reported.

A distinct freshwater-adapted subgroup of ANME-1 dominates active archaeal communities in terrestrial subsurfaces in Japan.

Anaerobic methane-oxidizing archaea (ANME) are known to play an important role in methane flux, especially in marine sediments. The 16S rRNA genes of ANME have been detected in terrestrial freshwater subsurfaces. However, it is unclear whether ANME are actively involved in methane oxidation in these environments.

Identification of G protein-coupled receptor 120-selective agonists derived from PPARgamma agonists.

A weak, nonselective G protein-coupled receptor 120 (GPR120) agonist 10 was found by screening a series of carboxylic acids derived from the peroxisome proliferator-activated receptor gamma (PPARgamma) agonist 3. Modification based on the homology model of GPR120 led to the first GPR120-selective agonist 12. These results provide a basis for constructing new tools for probing the biology of GPR120 and for developing new candidate therapeutic agents.

[Two cases of allergic granulomatosis and angiitis (AGA); Churg-Strauss syndrome].

AGA is an angiitis syndrome that has some characteristic features, for example preceding asthma and polyneuritis. And histological findings are granulomatous angiitis or extravascular granuloma. We report two typical cases of AGA.

Receptors for IgG Fc and complement in the mammalian aorta.

The presence of IgG Fc receptors in the tissue sections of aorta and aortic valves of man, ox and pig was demonstrated by means of hemadsorption of human and rabbit IgG antibody sensitized erythrocytes to these sections. C3b receptors in the tissue sections of aortic valves of these three mammals were also demonstrated by using sheep erythrocytes sensitized with rabbit IgM antibody which bound murine complement. 8 of 13 systemic lupus erythematosus sera and 2 of 19 other collagen disease sera were shown to be able to inhibit the adsorption of rabbit IgG antibody sensitized erythrocytes to the human aortic sections upon preincubation of the tissues with the pathologic sera.