Synopsis of recent research by authors named "Ifeoma Okwor"
- Ifeoma Okwor's research primarily focuses on the immune response mechanisms involved in allergic asthma and leishmaniasis, particularly emphasizing the roles of dendritic cells, macrophages, and specific proteins such as Sema3E and PlexinD1 in modulating inflammation and immune responses.
- Recent studies have indicated that deficiencies in PlexinD1 and Sema3E can exacerbate asthma symptoms and worsen the inflammatory response in both acute and chronic asthma models, highlighting the significance of these molecular pathways in allergic conditions.
- Okwor's work also delves into the complexities of leishmaniasis, exploring immune mechanisms that drive protective immunity, the impact of regulatory T cells, and the identification of potential vaccine targets by investigating conserved antigens and their responses in CD4+ T cells.