Holistic application of the one health approach in the prevention and control of rabies: plausible steps towards achieving the 2030 vision in Africa.

Rabies remains a significant public health challenge in Africa, primarily burdening impoverished rural communities, with children and young adults being the most vulnerable. Achieving complete elimination in the continent by 2030 requires a coordinated effort hinged on the One Health concept, external support from international organizations like the World Health Organization (WHO) and the national governments of endemic countries. Here, we reviewed the various socio-economic and ecological factors influencing the spatial distribution and molecular epidemiology of the disease.

The potential application of artificial intelligence in veterinary clinical practice and biomedical research.

Artificial intelligence (AI) is a fast-paced technological advancement in terms of its application to various fields of science and technology. In particular, AI has the potential to play various roles in veterinary clinical practice, enhancing the way veterinary care is delivered, improving outcomes for animals and ultimately humans. Also, in recent years, the emergence of AI has led to a new direction in biomedical research, especially in translational research with great potential, promising to revolutionize science.

Epidemiology and Transmission Dynamics of Viral Encephalitides in West Africa.

Encephalitis is an inflammation of the brain, often caused by an autoimmune reaction, or in most cases because of a direct viral, bacterial, or parasitic infection. Viral encephalitides (VE) presents a significant public health concern globally, especially in West Africa. There are more than five hundred known arthropod-borne viruses (arboviruses), with over a hundred of them identified to cause encephalitic diseases in humans and animals, giving rise to a tremendous burden of the diseases and socioeconomic strains in tropical and subtropical regions worldwide.

Crosstalk between hypoxic cellular micro-environment and the immune system: a potential therapeutic target for infectious diseases.

There are overwhelming reports on the promotional effect of hypoxia on the malignant behavior of various forms of cancer cells. This has been proposed and tested exhaustively in the light of cancer immunotherapy. However, there could be more interesting functions of a hypoxic cellular micro-environment than malignancy.

Usutu virus: An emerging flavivirus with potential threat to public health in Africa: Nigeria as a case study.

Usutu virus (USUV) is an arthropod-borne virus (arbovirus) of the flaviviridae family (genus ) which belong to the Japanese encephalitis virus complex. Culex mosquitoes have been implicated in the transmission of this pathogen. The major susceptible hosts of USUV are migratory birds, thereby potentiating its ability to spread from one region to another globally.