Topographical impact of silver nanolines on the morphology of neuronal SH-SY5Y Cells.

An extracellular environment is critical in neuronal development and growth. Changes in neuronal morphology, neuron adhesion, and even the rate of neurite formation, can be modified by both the chemical and physical properties of interfacing substrates. Topography has a major impact on neuronal growth.

Sonochemically-fabricated Ga@C-dots@Ga nanoparticle-aided neural growth.

In this paper, we report the fabrication of an antibacterial material, Ga-doped C-dots on Ga nanoparticles (Ga@C-dots@Ga NPs), which is deposited on a glass substrate for neural growth. A one-step sonochemical process is applied for the simultaneous fabrication and coating of Ga@C-dots@Ga NPs using PEG 400 and molten gallium. The physical and chemical characteristics of the synthesized materials were studied using scanning electron microscopy (SEM), transmission electron microscopy (TEM), energy dispersive X-ray spectroscopy (EDS), fluorescence analysis, dynamic light scattering (DLS) and other techniques.

Substrates coated with silver nanoparticles as a neuronal regenerative material.

Much effort has been devoted to the design of effective biomaterials for nerve regeneration. Here, we report the novel use of silver nanoparticles (AgNPs) as regenerative agents to promote neuronal growth. We grew neuroblastoma cells on surfaces coated with AgNPs and studied the effect on the development of the neurites during the initiation and the elongation growth phases.