Sevoflurane and desflurane effects on early cognitive function after low-risk surgery: A randomized clinical trial.

Background And Objectives: Deleterious effects on short-term and long-term quality of life have been associated with the development of postoperative cognitive dysfunction (POCD) after general anesthesia. Yet, the progress in the field is still required. Most of the studies investigate POCD after major surgery, so scarce evidence exists about the incidence and effect different anesthetics have on POCD development after minor procedures.

Effects of sevoflurane and desflurane on early cognitive changes after thyroid surgery: interim results.

Unlabelled: The study is being conducted at the 1st Department of Anaesthesiology, the Centre of Abdominal Surgery, the Centre of Anaesthesiology, Intensive Care and Pain Management of Vilnius University Hospital Santaros Klinikos.

Background: These are primary results of a randomized double-blinded study comparing postoperative changes in cognitive functions and the effect of desflurane and sevoflurane on these changes.

Materials And Methods: The study includes patients of ≥40 years of age undergoing elective thyroid surgery under general anaesthesia.