[Solid pseudopapillary epithelial pancreatic tumor].

Solid pseudopapillary pancreatic neoplasm-is a tumor, which appears rarely, predominantly in young women, has low malignant potential and unknown histogenesis. Morphological peculiarities of the tumor may be the same as in endocrinal tumors and ductal pancreatic adenocarcinoma, with which it must be differed. Immunohistochemical investigation of the tumor does not permit to obtain information for strict diferential diagnosis conduction; macroscopic and microscopic peculiarities of the tumor while staining with hematoxilin and eosin give more important information for its diagnosis.

[Metabolic disorders after performance of total pancreatectomy].

The literature data concerning metabolic disorders after performance of total pancreatectomy and the results of analysis of this intervention, done in 2003-2004 yrs in 4 patients are presented.

[Analysis of immediate complications and mortality after performance of pancreatic resection].

Experience of performance of pancreatic resection during two years in the clinic was summarized. In 90.4% of patients there was revealed malignant tumor, as a rule, in III-IV stage, complicated by jaundice, gastrointestinal bleeding and ileus.

[Ethanol injections in the integrated treatment of non-resectable malignant pancreatic tumor complicated by jaundice].

Results of treatment were analyzed in 28 patients with nonresectable pancreatic cancer (III-IV stages) complicated by jaundice, to whom in complex of treatment (biliodigestive shunting, in some of patients with hepatic dearterialyzation, gastroenterostomy, pancreatodigestive shunting) 96% ethanol was injected into the tumor. The complications frequency had constituted 21.4%, mortality--14.

[Hemocoagulation disorder in patients with destructive pancreatitis: the role in pathogenesis and ways of its correction].

The dynamics of hemocoagulation system changes in patients with different clinical forms of destructive pancreatitis (DP) was evaluated. The necessity of use of directed hemocoagulation therapy and hemocorrection, in particular, the use of low-molecular weight heparins, in complex program of treatment of DP is proved.

[A comparative analysis of changes in immune homeostasis in laparoscopic and conventional surgical interventions on the large intestine].

A comprehensive evaluation has been done of parameters characterizing cell-bound immunity, cytokinic profile, stress hormones (hydrocortisone), and C-reactive protein in a comparative aspect in those patients having undergone laparoscopic or conventional colectomy. The above indices were determined before surgery, in the early postoperative period, 24 h and 7 days subsequent to surgery. Laparoscopic surgical intervention was found out to lower somewhat the level of immunosuppression early in the postoperative course, which fact is manifested by retaining of expression HLA-DR on monocytes of the peripheral blood.

[Lipid peroxidation, the antioxidant system and the trace element level in acute pancreatitis].

Overall, thirty-two patients with acute pancreatitis (edematous, destructive, purulent forms) were studied for the state of lipid peroxidation (LPO), antioxidant defence (AOD), and trace element status. The development of destructive and purulent forms of acute pancreatitis was found out to be accompanied by activation of LPO processes, AOD breakdown, with profound disturbances having been disclosed in the metabolism of zinc, selenium, cuprum, manganum, that play an important part in LPO, AOD processes, and in those of immune defence. The secured results suggest that there is a need for us to include into a complex therapy of acute pancreatitis antioxidants and some trace elements (zinc, celenium) and that it is expedient to use indices for the LPO, AOD systems, and for trace element status in the differential diagnosis of clinical forms of acute pancreatitis, prognostication of development of purulent complications.