Turning Data to Knowledge: Online Tools, Databases, and Resources in microRNA Research.

MicroRNAs (miRNAs) provide a fundamental layer of regulation in cells. miRNAs act posttranscriptionally through complementary base-pairing with the 3'-UTR of a target mRNA, leading to mRNA degradation and translation arrest. The likelihood of forming a valid miRNA-target duplex within cells was computationally predicted and experimentally monitored.

Revisiting the Risk Factors for Endometriosis: A Machine Learning Approach.

Endometriosis is a condition characterized by implants of endometrial tissues into extrauterine sites, mostly within the pelvic peritoneum. The prevalence of endometriosis is under-diagnosed and is estimated to account for 5-10% of all women of reproductive age. The goal of this study was to develop a model for endometriosis based on the UK-biobank (UKB) and re-assess the contribution of known risk factors to endometriosis.

Significantly Improved COVID-19 Outcomes in Countries with Higher BCG Vaccination Coverage: A Multivariable Analysis.

The COVID-19 pandemic that started in China has spread within 3 months to the entire globe. We tested the hypothesis that the vaccination against tuberculosis by Bacille Calmette-Guérin vaccine (BCG) correlates with a better outcome for COVID-19 patients. Our analysis covers 55 countries complying with predetermined thresholds on the population size and number of deaths per million (DPM).