Publications by authors named "Idanya Rubi Serafin Higuera"

Background: A lack of high-quality provider education hinders the delivery of standard-of-care delirium detection and prevention practices in the intensive care unit (ICU). To fill this gap, we developed and validated an e-learning ICU Delirium Playbook consisting of eight videos and a 44-question knowledge assessment quiz. Given the increasing Spanish-speaking population worldwide, we translated and cross-culturally adapted the playbook from English into Spanish.

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Between March 2020 and February 2021, the state of Baja California, Mexico, which borders the United States, registered 46,118 confirmed cases of COVID-19 with a mortality rate of 238.2 deaths per 100,000 residents. Given limited access to testing, the population prevalence of SARS-CoV-2 infection is unknown.

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Article Synopsis
  • Research investigated the cytotoxic effects of hexane, chloroform, and methanol extracts from roots on various cancer cell lines, with hexane extract showing the highest activity (IC of 10.6 µg mL).
  • Three diterpenoids were isolated from the hexane extract and tested for their effects on cancer cells: one showed moderate activity while another was practically inactive.
  • The active compound was found to induce arrest in the G0/G1 phase of the cell cycle, likely through DNA damage, and also reduced cell migration in specific cancer cells.
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